{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["32(1)"],"submitter":["Michikawa T"],"pubmed_abstract":["<h4>Background</h4>Maternal exposure to fine particulate matter (PM<sub>2.5</sub>) was associated with pregnancy complications. However, we still lack comprehensive evidence regarding which specific chemical components of PM<sub>2.5</sub> are more harmful for maternal and foetal health.<h4>Objective</h4>We focused on exposure over the first trimester (0-13 weeks of gestation), which includes the early placentation period, and investigated whether PM<sub>2.5</sub> and its components were associated with placenta-mediated pregnancy complications (combined outcome of small for gestational age, preeclampsia, placental abruption, and stillbirth).<h4>Methods</h4>From 2013 to 2015, we obtained information, from the Japan Perinatal Registry Network database, on 83,454 women who delivered singleton"],"journal":["Journal of exposure science & environmental epidemiology"],"pagination":["135-145"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8770113"],"repository":["biostudies-literature"],"pubmed_title":["Exposure to chemical components of fine particulate matter and ozone, and placenta-mediated pregnancy complications in Tokyo: a register-based study."],"pmcid":["PMC8770113"],"pubmed_authors":["Saito S","Nitta H","Morokuma S","Yoshino A","Takeda Y","Nakahara K","Michikawa T","Kato K","Nishiwaki Y","Sugata S","Hoshi J","Yamazaki S","Takami A"],"additional_accession":[]},"is_claimable":false,"name":"Exposure to chemical components of fine particulate matter and ozone, and placenta-mediated pregnancy complications in Tokyo: a register-based study.","description":"<h4>Background</h4>Maternal exposure to fine particulate matter (PM<sub>2.5</sub>) was associated with pregnancy complications. However, we still lack comprehensive evidence regarding which specific chemical components of PM<sub>2.5</sub> are more harmful for maternal and foetal health.<h4>Objective</h4>We focused on exposure over the first trimester (0-13 weeks of gestation), which includes the early placentation period, and investigated whether PM<sub>2.5</sub> and its components were associated with placenta-mediated pregnancy complications (combined outcome of small for gestational age, preeclampsia, placental abruption, and stillbirth).<h4>Methods</h4>From 2013 to 2015, we obtained information, from the Japan Perinatal Registry Network database, on 83,454 women who delivered singleton","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-04T21:33:44.452Z","creation":"2025-04-04T21:33:44.452Z"},"accession":"S-EPMC8770113","cross_references":{"pubmed":["33603097"],"doi":["10.1038/s41370-021-00299-4"]}}