{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(2)"],"submitter":["Simonsen AK"],"pubmed_abstract":["Bacteria have highly flexible pangenomes, which are thought to facilitate evolutionary responses to environmental change, but the impacts of environmental stress on pangenome evolution remain unclear. Using a landscape pangenomics approach, I demonstrate that environmental stress leads to consistent, continuous reduction in genome content along four environmental stress gradients (acidity, aridity, heat, salinity) in naturally occurring populations of Bradyrhizobium diazoefficiens (widespread soil-dwelling plant mutualists). Using gene-level network and duplication functional traits to predict accessory gene distributions across environments, genes predicted to be superfluous are more likely lost in high stress, while genes with multi-functional roles are more likely retained. Genes with h"],"journal":["The ISME journal"],"pagination":["423-434"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8776746"],"repository":["biostudies-literature"],"pubmed_title":["Environmental stress leads to genome streamlining in a widely distributed species of soil bacteria."],"pmcid":["PMC8776746"],"pubmed_authors":["Simonsen AK"],"additional_accession":[]},"is_claimable":false,"name":"Environmental stress leads to genome streamlining in a widely distributed species of soil bacteria.","description":"Bacteria have highly flexible pangenomes, which are thought to facilitate evolutionary responses to environmental change, but the impacts of environmental stress on pangenome evolution remain unclear. Using a landscape pangenomics approach, I demonstrate that environmental stress leads to consistent, continuous reduction in genome content along four environmental stress gradients (acidity, aridity, heat, salinity) in naturally occurring populations of Bradyrhizobium diazoefficiens (widespread soil-dwelling plant mutualists). Using gene-level network and duplication functional traits to predict accessory gene distributions across environments, genes predicted to be superfluous are more likely lost in high stress, while genes with multi-functional roles are more likely retained. Genes with h","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2026-05-09T03:01:07.037Z","creation":"2025-04-06T14:57:34.453Z"},"accession":"S-EPMC8776746","cross_references":{"pubmed":["34408268"],"doi":["10.1038/s41396-021-01082-x"]}}