{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Montomoli E"],"funding":["Italian Association for Cancer Research","Fondazione IRCCS Istituto Nazionale dei Tumori"],"pagination":["61"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8778320"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["The massive emergence of COVID-19 cases in the first phase of pandemic within an extremely short period of time suggest that an undetected earlier circulation of SARS-CoV-2 might have occurred. Given the importance of this evidence, an independent evaluation was recommended by the World Health Organization (WHO) to test a subset of samples selected on the level of positivity in ELISA assays (positive, low positive, negative) detected in our previous study of prepandemic samples collected in Italy. SARS-CoV-2 antibodies were blindly retested by two independent centers in 29 blood samples collected in the prepandemic period in Italy, 29 samples collected one year before and 11 COVID-19 control samples. The methodologies used included IgG-RBD/IgM-RBD ELISA assays, a qualitative micro-neutrali"],"journal":["Viruses"],"pubmed_title":["Timeline of SARS-CoV-2 Spread in Italy: Results from an Independent Serological Retesting."],"pmcid":["PMC8778320"],"funding_grant_id":["N/A","12162"],"pubmed_authors":["Suatoni P","Apolone G","Sabia F","Pastorino U","Boeri M","Marchiano A","Manenti A","Sozzi G","Montomoli E","Bollati V"],"additional_accession":[]},"is_claimable":false,"name":"Timeline of SARS-CoV-2 Spread in Italy: Results from an Independent Serological Retesting.","description":"The massive emergence of COVID-19 cases in the first phase of pandemic within an extremely short period of time suggest that an undetected earlier circulation of SARS-CoV-2 might have occurred. Given the importance of this evidence, an independent evaluation was recommended by the World Health Organization (WHO) to test a subset of samples selected on the level of positivity in ELISA assays (positive, low positive, negative) detected in our previous study of prepandemic samples collected in Italy. SARS-CoV-2 antibodies were blindly retested by two independent centers in 29 blood samples collected in the prepandemic period in Italy, 29 samples collected one year before and 11 COVID-19 control samples. The methodologies used included IgG-RBD/IgM-RBD ELISA assays, a qualitative micro-neutrali","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-21T17:34:33.311Z","creation":"2022-02-11T15:51:06.063Z"},"accession":"S-EPMC8778320","cross_references":{"pubmed":["35062265"],"doi":["10.3390/v14010061"]}}