biostudies-literatureJankowitz BTStryker Neurovascular143-148https://www.ebi.ac.uk/biostudies/studies/S-EPMC8785011biostudies-literatureUnknown14(2)<h4>Background</h4>Stent-assisted coiling of wide-necked intracranial aneurysms (IAs) using the Neuroform Atlas Stent System (Atlas) has shown promising results.<h4>Objective</h4>To present the primary efficacy and safety results of the ATLAS Investigational Device Exemption (IDE) trial in a cohort of patients with posterior circulation IAs.<h4>Methods</h4>The ATLAS trial is a prospective, multicenter, single-arm, open-label study of unruptured, wide-necked, IAs treated with the Atlas stent and adjunctive coiling. This study reports the results of patients with posterior circulation IAs. The primary efficacy endpoint was complete aneurysm occlusion (Raymond-Roy (RR) class I) on 12-month angiography, in the absence of re-treatment or parent artery stenosis >50%. The primary safety endpoint Journal of neurointerventional surgeryPivotal trial of the Neuroform Atlas stent for treatment of posterior circulation aneurysms: one-year outcomes.PMC8785011Industry funded with no grant.Hallam DKJankowitz BTThomas AFraser JFZaidat OOSiddiqui AHCrowley RWReavey-Cantwell JTurk ASKlucznik RCaplan JMColby GPAlhajeri AAFrei DSpiotta AMToth GBellon RLopes DKFroehler MTAghaebrahim APuri ASArthur ASKan PSatti SRKhaldi AMalek AMCallison RCSauvageau EJadhav APGross BHanel RALin EKung DLoy DAlexander MJJovin TGHetts SWfalsePivotal trial of the Neuroform Atlas stent for treatment of posterior circulation aneurysms: one-year outcomes.<h4>Background</h4>Stent-assisted coiling of wide-necked intracranial aneurysms (IAs) using the Neuroform Atlas Stent System (Atlas) has shown promising results.<h4>Objective</h4>To present the primary efficacy and safety results of the ATLAS Investigational Device Exemption (IDE) trial in a cohort of patients with posterior circulation IAs.<h4>Methods</h4>The ATLAS trial is a prospective, multicenter, single-arm, open-label study of unruptured, wide-necked, IAs treated with the Atlas stent and adjunctive coiling. This study reports the results of patients with posterior circulation IAs. The primary efficacy endpoint was complete aneurysm occlusion (Raymond-Roy (RR) class I) on 12-month angiography, in the absence of re-treatment or parent artery stenosis >50%. The primary safety endpoint 2022-01-01T00:00:00Z2022 Feb2026-06-07T07:30:17.233Z2025-04-04T07:52:10.917ZS-EPMC87850113372296110.1136/neurintsurg-2020-017115