biostudies-literatureNelson KEEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNICHD NIH HHSAgency for Healthcare Research and QualityThe Hospital for Sick ChildrenAHRQ HHS782-788https://www.ebi.ac.uk/biostudies/studies/S-EPMC8786975biostudies-literatureUnknown22(5)<h4>Objective</h4>To assess the performance of previously published high-intensity neurologic impairment (NI) diagnosis codes in identification of hospitalized children with clinical NI.<h4>Methods</h4>Retrospective study of 500 randomly selected discharges in 2019 from a freestanding children's hospital. All charts were reviewed for 1) NI discharge diagnosis codes and 2) documentation of clinical NI (a neurologic diagnosis and indication of functional impairment like medical technology). Test statistics of clinical NI were calculated for discharges with and without an NI diagnosis code. A sensitivity analysis varied the threshold for "substantial functional impairment." Secondary analyses evaluated misclassified discharges and a more stringent definition for NI.<h4>Results</h4>Diagnosis cAcademic pediatricsValidation of Neurologic Impairment Diagnosis Codes as Signifying Documented Functional Impairment in Hospitalized Children.PMC8786975K23 HD091295K08 HS025138Nelson KEFeinstein JAThomson JDiskin CFeudtner CChakravarti VWidger KPullenayegum ECohen EBerry JGMahant SfalseValidation of Neurologic Impairment Diagnosis Codes as Signifying Documented Functional Impairment in Hospitalized Children.<h4>Objective</h4>To assess the performance of previously published high-intensity neurologic impairment (NI) diagnosis codes in identification of hospitalized children with clinical NI.<h4>Methods</h4>Retrospective study of 500 randomly selected discharges in 2019 from a freestanding children's hospital. All charts were reviewed for 1) NI discharge diagnosis codes and 2) documentation of clinical NI (a neurologic diagnosis and indication of functional impairment like medical technology). Test statistics of clinical NI were calculated for discharges with and without an NI diagnosis code. A sensitivity analysis varied the threshold for "substantial functional impairment." Secondary analyses evaluated misclassified discharges and a more stringent definition for NI.<h4>Results</h4>Diagnosis c2022-01-01T00:00:00Z2022 Jul2025-04-26T07:40:29.146Z2025-04-06T12:21:40.048ZS-EPMC87869753432041410.1016/j.acap.2021.07.014