{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hong L"],"funding":["Swiss National Science Foundation","Project of Tianjin Science and Technology Plan","Open Project Program of State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology","National Natural Science Foundation of China"],"pagination":["51"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8787952"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["In this study, a thermo-sensitive molecularly imprinted fluorescence sensor was developed for the specific detection of β-Lactoglobulin (β-LG) allergen in milk products. The metal-organic frameworks (MIL-100) with a high specific surface area was coated on the surface of upconversion micro-particles (UCMPs). As the core, an imprinted polymer layer allowing for swelling and shrinking with response to temperature was prepared, which exhibited high adsorption and mass transfer capabilities for β-LG allergen. The fluorescence intensity of UCMPs@MIL-100@MIP decreased linearly with the concentration of β-LG in the range of 0.1-0.8 mg mL<sup>-1</sup>, and the limit of detection was 0.043 mg mL<sup>-1</sup>. The imprinting factor reached 3.415, which indicated that excellent specificity of the UCM"],"journal":["Journal of nanobiotechnology"],"pubmed_title":["A UCMPs@MIL-100 based thermo-sensitive molecularly imprinted fluorescence sensor for effective detection of β-lactoglobulin allergen in milk products."],"pmcid":["PMC8787952"],"funding_grant_id":["No. SKLFNS-KF-202115","No. 20ZYJDJC00040","No. 31972147","202115"],"pubmed_authors":["Hong L","Yang X","Yang J","Liu K","Xie X","Wang S","Pan M"],"additional_accession":[]},"is_claimable":false,"name":"A UCMPs@MIL-100 based thermo-sensitive molecularly imprinted fluorescence sensor for effective detection of β-lactoglobulin allergen in milk products.","description":"In this study, a thermo-sensitive molecularly imprinted fluorescence sensor was developed for the specific detection of β-Lactoglobulin (β-LG) allergen in milk products. The metal-organic frameworks (MIL-100) with a high specific surface area was coated on the surface of upconversion micro-particles (UCMPs). As the core, an imprinted polymer layer allowing for swelling and shrinking with response to temperature was prepared, which exhibited high adsorption and mass transfer capabilities for β-LG allergen. The fluorescence intensity of UCMPs@MIL-100@MIP decreased linearly with the concentration of β-LG in the range of 0.1-0.8 mg mL<sup>-1</sup>, and the limit of detection was 0.043 mg mL<sup>-1</sup>. The imprinting factor reached 3.415, which indicated that excellent specificity of the UCM","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-04T08:34:18.353Z","creation":"2025-04-04T08:34:18.353Z"},"accession":"S-EPMC8787952","cross_references":{"pubmed":["35078480"],"doi":["10.1186/s12951-022-01258-3"]}}