{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chang SH"],"funding":["National Cancer Institute","NCI NIH HHS"],"pagination":["e1365-e1377"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8789949"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(6)"],"pubmed_abstract":["<h4>Background & aims</h4>Colorectal cancer (CRC) incidence has decreased overall in the last several decades, but it has increased among younger adults. Prior studies have characterized this phenomenon in the United States (U.S.) using only a small subset of cases. We describe CRC incidence trends using high-quality data from 92% of the U.S. population, with an emphasis on those younger than 50 years.<h4>Methods</h4>We obtained 2001 to 2016 data from the U.S. Cancer Statistics database and analyzed CRC incidence for all age groups, with a focus on individuals diagnosed at ages 20 to 49 years (early-onset CRC). We compared incidence trends stratified by age, as well as by race/ethnicity, sex, region, anatomic site, and stage at diagnosis.<h4>Results</h4>We observed 191,659 cases of early-o"],"journal":["Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association"],"pubmed_title":["Trends in Early-onset vs Late-onset Colorectal Cancer Incidence by Race/Ethnicity in the United States Cancer Statistics Database."],"pmcid":["PMC8789949"],"funding_grant_id":["P30 CA008748","K08 CA230162"],"pubmed_authors":["Patel N","Chang SH","Liang PS","Du M"],"additional_accession":[]},"is_claimable":false,"name":"Trends in Early-onset vs Late-onset Colorectal Cancer Incidence by Race/Ethnicity in the United States Cancer Statistics Database.","description":"<h4>Background & aims</h4>Colorectal cancer (CRC) incidence has decreased overall in the last several decades, but it has increased among younger adults. Prior studies have characterized this phenomenon in the United States (U.S.) using only a small subset of cases. We describe CRC incidence trends using high-quality data from 92% of the U.S. population, with an emphasis on those younger than 50 years.<h4>Methods</h4>We obtained 2001 to 2016 data from the U.S. Cancer Statistics database and analyzed CRC incidence for all age groups, with a focus on individuals diagnosed at ages 20 to 49 years (early-onset CRC). We compared incidence trends stratified by age, as well as by race/ethnicity, sex, region, anatomic site, and stage at diagnosis.<h4>Results</h4>We observed 191,659 cases of early-o","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2025-04-21T21:51:19.855Z","creation":"2025-04-21T21:51:19.855Z"},"accession":"S-EPMC8789949","cross_references":{"pubmed":["34325062"],"doi":["10.1016/j.cgh.2021.07.035"]}}