{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gammie JS"],"funding":["NCATS NIH HHS","Deutsches Zentrum für Herz-Kreislaufforschung","National Heart, Lung, and Blood Institute","NHLBI NIH HHS"],"pagination":["327-339"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8796794"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["386(4)"],"pubmed_abstract":["<h4>Background</h4>Tricuspid regurgitation is common in patients with severe degenerative mitral regurgitation. However, the evidence base is insufficient to inform a decision about whether to perform tricuspid-valve repair during mitral-valve surgery in patients who have moderate tricuspid regurgitation or less-than-moderate regurgitation with annular dilatation.<h4>Methods</h4>We randomly assigned 401 patients who were undergoing mitral-valve surgery for degenerative mitral regurgitation to receive a procedure with or without tricuspid annuloplasty (TA). The primary 2-year end point was a composite of reoperation for tricuspid regurgitation, progression of tricuspid regurgitation by two grades from baseline or the presence of severe tricuspid regurgitation, or death.<h4>Results</h4>Patie"],"journal":["The New England journal of medicine"],"pubmed_title":["Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation."],"pmcid":["PMC8796794"],"funding_grant_id":["N/A","U01 HL088942","UM1 HL117924","UL1 TR001863","UM1 HL088955"],"pubmed_authors":["Hong-Zohlman S","Glower D","Dobrev E","Miller MA","Gervais N","Nelavelli L","Lane K","Petty G","Phelan D","Fagu A","Birru H","Pingpoh C","Moquete EG","Siemienik A","O'Gara PT","Pfannmuller B","Possemato T","Scheida I","Romano MA","Mathewson S","Demal T","Becher H","Vesom N","Sidhu S","Pellerin M","Dunagan B","Dobrev V","Bhave N","Yancy CW","Leinberger T","Fisher T","Treffalls J","Gayburn P","Alborzi F","Sturgis L","McCarty D","Santos M","Ye X","Baer J","Boileau C","Lala 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F","McBride M","Lam S","Pausch J","Ajala Fuentes R","Garceau P","Stojanoska E"],"additional_accession":[]},"is_claimable":false,"name":"Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation.","description":"<h4>Background</h4>Tricuspid regurgitation is common in patients with severe degenerative mitral regurgitation. However, the evidence base is insufficient to inform a decision about whether to perform tricuspid-valve repair during mitral-valve surgery in patients who have moderate tricuspid regurgitation or less-than-moderate regurgitation with annular dilatation.<h4>Methods</h4>We randomly assigned 401 patients who were undergoing mitral-valve surgery for degenerative mitral regurgitation to receive a procedure with or without tricuspid annuloplasty (TA). The primary 2-year end point was a composite of reoperation for tricuspid regurgitation, progression of tricuspid regurgitation by two grades from baseline or the presence of severe tricuspid regurgitation, or death.<h4>Results</h4>Patie","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2026-05-09T22:18:41.011Z","creation":"2025-04-26T13:06:00.039Z"},"accession":"S-EPMC8796794","cross_references":{"pubmed":["34767705"],"doi":["10.1056/NEJMoa2115961","10.1056/nejmoa2115961"]}}