{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Fajrial AK"],"funding":["University of Colorado Boulder","W. M. Keck Foundation","National Institutes of Health","NIGMS NIH HHS"],"pagination":["4772-4778"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8805482"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["21(24)"],"pubmed_abstract":["Manipulation of fluid flow is paramount for microfluidic device operation. Conventional microfluidic pumps are often expensive, bulky, complicated, and not amenable in limited resource settings. Here, we introduce a Fully self-sufficient, RobUst, Gravity-Assisted, Low-cost (FRUGAL) microfluidic pump. The pump consists of a syringe, a syringe holder and loading masses. The system is easy to assemble, inexpensive, portable, and electrical power-free. Inside the syringe, the fluid is driven by the pressure from the weight of the loading masses. During operation, the exerted pressure is dynamically controllable and stable for hours. These features are useful for optimization of microfluidics assays and dynamic temporal studies. We demonstrate the application of this system to control the forma"],"journal":["Lab on a chip"],"pubmed_title":["A frugal microfluidic pump."],"pmcid":["PMC8805482"],"funding_grant_id":["Startup Fund","Medical Research Grant","RGM142817A","R35 GM142817"],"pubmed_authors":["Fajrial AK","Ding X","Shakya G","Vega A"],"additional_accession":[]},"is_claimable":false,"name":"A frugal microfluidic pump.","description":"Manipulation of fluid flow is paramount for microfluidic device operation. Conventional microfluidic pumps are often expensive, bulky, complicated, and not amenable in limited resource settings. Here, we introduce a Fully self-sufficient, RobUst, Gravity-Assisted, Low-cost (FRUGAL) microfluidic pump. The pump consists of a syringe, a syringe holder and loading masses. The system is easy to assemble, inexpensive, portable, and electrical power-free. Inside the syringe, the fluid is driven by the pressure from the weight of the loading masses. During operation, the exerted pressure is dynamically controllable and stable for hours. These features are useful for optimization of microfluidics assays and dynamic temporal studies. We demonstrate the application of this system to control the forma","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-05T11:49:27.972Z","creation":"2025-04-05T11:49:27.972Z"},"accession":"S-EPMC8805482","cross_references":{"pubmed":["34751689"],"doi":["10.1039/d1lc00691f"]}}