{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["42(12)"],"submitter":["Cogswell PM"],"funding":["Theodore W. Batterman Family Foundation"],"pubmed_abstract":["<h4>Background and purpose</h4>While changes in ventricular and extraventricular CSF spaces have been studied following shunt placement in patients with idiopathic normal pressure hydrocephalus, regional changes in cortical volumes have not. These changes are important to better inform disease pathophysiology and evaluation for copathology. The purpose of this work is to investigate changes in ventricular and cortical volumes in patients with idiopathic normal pressure hydrocephalus following ventriculoperitoneal shunt placement.<h4>Materials and methods</h4>This is a retrospective cohort study of patients with idiopathic normal pressure hydrocephalus who underwent 3D T1-weighted MR imaging before and after ventriculoperitoneal shunt placement. Images were analyzed using tensor-based morph"],"journal":["AJNR. American journal of neuroradiology"],"pagination":["2165-2171"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8805754"],"repository":["biostudies-literature"],"pubmed_title":["Changes in Ventricular and Cortical Volumes following Shunt Placement in Patients with Idiopathic Normal Pressure Hydrocephalus."],"pmcid":["PMC8805754"],"pubmed_authors":["Elder BD","Graff-Radford J","Meyer FB","Gunter JL","Cutsforth-Gregory JK","Jack CR","Murphy MC","Botha H","Schwarz CG","Cogswell PM","Huston J","Jones DT","Senjem ML"],"additional_accession":[]},"is_claimable":false,"name":"Changes in Ventricular and Cortical Volumes following Shunt Placement in Patients with Idiopathic Normal Pressure Hydrocephalus.","description":"<h4>Background and purpose</h4>While changes in ventricular and extraventricular CSF spaces have been studied following shunt placement in patients with idiopathic normal pressure hydrocephalus, regional changes in cortical volumes have not. These changes are important to better inform disease pathophysiology and evaluation for copathology. The purpose of this work is to investigate changes in ventricular and cortical volumes in patients with idiopathic normal pressure hydrocephalus following ventriculoperitoneal shunt placement.<h4>Materials and methods</h4>This is a retrospective cohort study of patients with idiopathic normal pressure hydrocephalus who underwent 3D T1-weighted MR imaging before and after ventriculoperitoneal shunt placement. Images were analyzed using tensor-based morph","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-05T09:44:15.034Z","creation":"2025-04-05T09:44:15.034Z"},"accession":"S-EPMC8805754","cross_references":{"pubmed":["34674997"],"doi":["10.3174/ajnr.a7323","10.3174/ajnr.A7323"]}}