biostudies-literatureChamberlain ATNational Institute of Allergy and Infectious DiseasesCenter for AIDS Research at Emory UniversityNIAID NIH HHSEmory Covid-19 Response CollaborativeCalifornia Department of Health396-403https://www.ebi.ac.uk/biostudies/studies/S-EPMC8807152biostudies-literatureUnknown225(3)<h4>Background</h4>Reported coronavirus disease 2019 (COVID-19) cases underestimate true severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Data on all infections, including asymptomatic infections, are needed. To minimize biases in estimates from reported cases and seroprevalence surveys, we conducted a household-based probability survey and estimated cumulative incidence of SARS-CoV-2 infections adjusted for antibody waning.<h4>Methods</h4>From August to December 2020, we mailed specimen collection kits (nasal swabs and blood spots) to a random sample of Georgia addresses. One household adult completed a survey and returned specimens for virus and antibody testing. We estimated cumulative incidence of SARS-CoV-2 infections adjusted for waning antibodies, reported frThe Journal of infectious diseasesCumulative Incidence of SARS-CoV-2 Infections Among Adults in Georgia, United States, August to December 2020.PMC8807152R01 AI143875P30AI0504093R01AI143875-02S1Siegler AJSullivan PSChamberlain ATShioda KHall EWFahimi MLopman BASanchez TBradley HDrenzek CLuisi NToomey KEfalseCumulative Incidence of SARS-CoV-2 Infections Among Adults in Georgia, United States, August to December 2020.<h4>Background</h4>Reported coronavirus disease 2019 (COVID-19) cases underestimate true severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Data on all infections, including asymptomatic infections, are needed. To minimize biases in estimates from reported cases and seroprevalence surveys, we conducted a household-based probability survey and estimated cumulative incidence of SARS-CoV-2 infections adjusted for antibody waning.<h4>Methods</h4>From August to December 2020, we mailed specimen collection kits (nasal swabs and blood spots) to a random sample of Georgia addresses. One household adult completed a survey and returned specimens for virus and antibody testing. We estimated cumulative incidence of SARS-CoV-2 infections adjusted for waning antibodies, reported fr2022-01-01T00:00:00Z2022 Feb2026-05-08T10:36:00.725Z2025-02-19T01:47:04.046ZS-EPMC88071523466240910.1093/infdis/jiab522