biostudies-literatureUnknown1(4)Molony DA<h4>Background</h4>Combination therapy with multiple phosphate binders is prescribed to reduce elevated serum phosphorus (sP) concentrations among patients on maintenance hemodialysis. Sucroferric oxyhydroxide (SO), an iron-based phosphate binder, has demonstrated efficacy at reducing sP while also being associated with a low pill burden. Whereas the effects of SO monotherapy have been well characterized in clinical trials and observational cohorts, little is known about the effects of SO-containing combination therapy.<h4>Methods</h4>Patients on hemodialysis (<i>N</i>=234) at Fresenius Kidney Care (FKC) who received ≥120 days of uninterrupted phosphate binder combination therapy with SO were included in this retrospective study. Patient data were censored after SO discontinuation, end of Kidney360263-272https://www.ebi.ac.uk/biostudies/studies/S-EPMC8809266biostudies-literatureSucroferric Oxyhydroxide as Part of Combination Phosphate Binder Therapy among Hemodialysis Patients.PMC8809266Parameswaran VMolony DAKossmann RJFicociello LHMullon CfalseSucroferric Oxyhydroxide as Part of Combination Phosphate Binder Therapy among Hemodialysis Patients.<h4>Background</h4>Combination therapy with multiple phosphate binders is prescribed to reduce elevated serum phosphorus (sP) concentrations among patients on maintenance hemodialysis. Sucroferric oxyhydroxide (SO), an iron-based phosphate binder, has demonstrated efficacy at reducing sP while also being associated with a low pill burden. Whereas the effects of SO monotherapy have been well characterized in clinical trials and observational cohorts, little is known about the effects of SO-containing combination therapy.<h4>Methods</h4>Patients on hemodialysis (<i>N</i>=234) at Fresenius Kidney Care (FKC) who received ≥120 days of uninterrupted phosphate binder combination therapy with SO were included in this retrospective study. Patient data were censored after SO discontinuation, end of 2020-01-01T00:00:00Z2020 Apr2025-04-04T03:20:06.177Z2025-04-04T03:20:06.177ZS-EPMC88092663537292110.34067/kid.000033201910.34067/KID.0000332019