biostudies-literatureUnknown8Lee SH<h4>Background</h4>This study investigated whether left ventricular (LV) global longitudinal strain (LV-GLS), as an LV function parameter less affected by mitral valve (MV) repair or prosthesis, is associated with clinical outcomes in patients with surgically treated MV disease.<h4>Methods</h4>Among 750 patients who underwent MV surgery, we assessed LV-GLS by speckle tracking echocardiography in 344 patients (148 men, mean age 58 ± 13 years) who showed preserved LV ejection fraction on echocardiography between 6 months and 2 years after MV surgery and who did not undergo aortic valve surgery. The assessed clinical events included admission for worsening of heart failure and cardiac death.<h4>Results</h4>During a period of 42.4 ± 26.0 months, 32 (9.3%) patients were hospitalized for worseniFrontiers in cardiovascular medicine775533https://www.ebi.ac.uk/biostudies/studies/S-EPMC8810643biostudies-literaturePrognostic Implications of Left Ventricular Global Longitudinal Strain in Patients With Surgically Treated Mitral Valve Disease and Preserved Ejection Fraction.PMC8810643Lhagvasuren PCho IKim DYHong GRSeo JLee SHHa JWShim CYfalsePrognostic Implications of Left Ventricular Global Longitudinal Strain in Patients With Surgically Treated Mitral Valve Disease and Preserved Ejection Fraction.<h4>Background</h4>This study investigated whether left ventricular (LV) global longitudinal strain (LV-GLS), as an LV function parameter less affected by mitral valve (MV) repair or prosthesis, is associated with clinical outcomes in patients with surgically treated MV disease.<h4>Methods</h4>Among 750 patients who underwent MV surgery, we assessed LV-GLS by speckle tracking echocardiography in 344 patients (148 men, mean age 58 ± 13 years) who showed preserved LV ejection fraction on echocardiography between 6 months and 2 years after MV surgery and who did not undergo aortic valve surgery. The assessed clinical events included admission for worsening of heart failure and cardiac death.<h4>Results</h4>During a period of 42.4 ± 26.0 months, 32 (9.3%) patients were hospitalized for worseni2021-01-01T00:00:00Z20212025-04-05T10:52:22.492Z2025-04-05T10:52:22.492ZS-EPMC88106433512785310.3389/fcvm.2021.775533