biostudies-literatureUnknown12Fouladseresht HShahid Beheshti University of Medical SciencesAlthough cellular and molecular mediators of the immune system have the potential to be prognostic indicators of disease outcomes, temporal interference between diseases might affect the immune mediators, and make them difficult to predict disease complications. Today one of the most important challenges is predicting the prognosis of COVID-19 in the context of other inflammatory diseases such as traumatic injuries. Many diseases with inflammatory properties are usually polyphasic and the kinetics of inflammatory mediators in various inflammatory diseases might be different. To find the most appropriate evaluation time of immune mediators to accurately predict COVID-19 prognosis in the trauma environment, researchers must investigate and compare cellular and molecular alterations based on Frontiers in immunology785946https://www.ebi.ac.uk/biostudies/studies/S-EPMC8815083biostudies-literaturePotential Immune Indicators for Predicting the Prognosis of COVID-19 and Trauma: Similarities and Disparities.PMC8815083Fouladseresht HEskandari NNorouzian MGhezelbash BBeyranvand MRNejadghaderi SASafiri SGhamar Talepoor AKolahi AACarson-Chahhoud KfalsePotential Immune Indicators for Predicting the Prognosis of COVID-19 and Trauma: Similarities and Disparities.Although cellular and molecular mediators of the immune system have the potential to be prognostic indicators of disease outcomes, temporal interference between diseases might affect the immune mediators, and make them difficult to predict disease complications. Today one of the most important challenges is predicting the prognosis of COVID-19 in the context of other inflammatory diseases such as traumatic injuries. Many diseases with inflammatory properties are usually polyphasic and the kinetics of inflammatory mediators in various inflammatory diseases might be different. To find the most appropriate evaluation time of immune mediators to accurately predict COVID-19 prognosis in the trauma environment, researchers must investigate and compare cellular and molecular alterations based on 2021-01-01T00:00:00Z20212025-04-25T17:12:35.374Z2025-04-06T04:02:57.316ZS-EPMC88150833512635510.3389/fimmu.2021.785946