{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dhakal P"],"funding":["National Institute of General Medical Sciences","NIGMS NIH HHS"],"pagination":["311-321"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8819600"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(3)"],"pubmed_abstract":["<b>Background:</b> We used the Therapy Preference Scale, a 30-item questionnaire, to determine cancer treatment preferences of adults with cancer. <b>Methods:</b> We used Wilcoxon's rank sum test and Fisher's exact test to compare the preferences of younger (<60 years) versus older adults (≥60 years). <b>Results:</b> While 56% of patients would accept treatment offering increased life expectancy at an expense of short-term side effects, 75% preferred maintenance of cognition, functional ability and quality of life to quantity of days. Oral instead of intravenous treatment (p = 0.003), shorter hospital stay (p = 0.03), preservation of cognitive function (p = 0.01) and avoidance of pain (p = 0.02) were more important to older patients compared with younger patients. <b>Conclusion:</b> Many patients prioritized maintenance of cognition, functional ability and quality of life; older patients valued oral treatment, shorter hospital stay, preservation of cognitive function and avoidance of pain."],"journal":["Future oncology (London, England)"],"pubmed_title":["Preferences of adults with cancer for systemic cancer treatment: do preferences differ based on age?"],"pmcid":["PMC8819600"],"funding_grant_id":["GM115458","U54 GM115458"],"pubmed_authors":["Wichman CS","Pozehl B","Bociek RG","Bhatt VR","Dhakal P","Vose J","Weaver M","Fisher AL"],"additional_accession":[]},"is_claimable":false,"name":"Preferences of adults with cancer for systemic cancer treatment: do preferences differ based on age?","description":"<b>Background:</b> We used the Therapy Preference Scale, a 30-item questionnaire, to determine cancer treatment preferences of adults with cancer. <b>Methods:</b> We used Wilcoxon's rank sum test and Fisher's exact test to compare the preferences of younger (<60 years) versus older adults (≥60 years). <b>Results:</b> While 56% of patients would accept treatment offering increased life expectancy at an expense of short-term side effects, 75% preferred maintenance of cognition, functional ability and quality of life to quantity of days. Oral instead of intravenous treatment (p = 0.003), shorter hospital stay (p = 0.03), preservation of cognitive function (p = 0.01) and avoidance of pain (p = 0.02) were more important to older patients compared with younger patients. <b>Conclusion:</b> Many patients prioritized maintenance of cognition, functional ability and quality of life; older patients valued oral treatment, shorter hospital stay, preservation of cognitive function and avoidance of pain.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-19T18:08:00.649Z","creation":"2025-04-19T18:08:00.649Z"},"accession":"S-EPMC8819600","cross_references":{"pubmed":["34761681"],"doi":["10.2217/fon-2021-0260"]}}