{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8"],"submitter":["Sanda M"],"pubmed_abstract":["<h4>Background</h4>Pyogenic vertebral osteomyelitis is a bacterial infection of the vertebral body that is often treatable with antibiotics, but some cases require additional surgical debridement of the infected tissue. Instrumentation is often utilized for stabilization of the spine as part of the surgical treatment, but controversy remains over the relative risks and benefits of acute instrumentation performed simultaneously with debridement versus delayed instrumentation performed days or weeks after debridement. The purpose of this review was to investigate the relative effects of acute and delayed instrumentation in treatment for pyogenic vertebral osteomyelitis on patient outcomes.<h4>Methods</h4>A PRISMA-compliant systematic literature review was conducted to identify studies publis"],"journal":["North American Spine Society journal"],"pagination":["100083"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8819946"],"repository":["biostudies-literature"],"pubmed_title":["The effect of instrumentation staging on patient outcomes in pyogenic vertebral osteomyelitis: A systematic review."],"pmcid":["PMC8819946"],"pubmed_authors":["Yim J","Sanda M","Andreshak T","Rahmani R","Singleton A","Sheffels E"],"additional_accession":[]},"is_claimable":false,"name":"The effect of instrumentation staging on patient outcomes in pyogenic vertebral osteomyelitis: A systematic review.","description":"<h4>Background</h4>Pyogenic vertebral osteomyelitis is a bacterial infection of the vertebral body that is often treatable with antibiotics, but some cases require additional surgical debridement of the infected tissue. Instrumentation is often utilized for stabilization of the spine as part of the surgical treatment, but controversy remains over the relative risks and benefits of acute instrumentation performed simultaneously with debridement versus delayed instrumentation performed days or weeks after debridement. The purpose of this review was to investigate the relative effects of acute and delayed instrumentation in treatment for pyogenic vertebral osteomyelitis on patient outcomes.<h4>Methods</h4>A PRISMA-compliant systematic literature review was conducted to identify studies publis","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-04T09:00:21.566Z","creation":"2025-04-04T09:00:21.566Z"},"accession":"S-EPMC8819946","cross_references":{"pubmed":["35141648"],"doi":["10.1016/j.xnsj.2021.100083"]}}