{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["4(1)"],"submitter":["Abou Fayad A"],"pubmed_abstract":["<h4>Objectives</h4>To investigate the acquired resistome in 18 colistin-resistant <i>Escherichia coli</i> isolated from different poultry farms in Lebanon, analyse Inc plasmids associated with <i>mcr</i> and assess potential transmission to humans.<h4>Methods</h4>A total of 18 <i>E. coli</i> were recovered from poultry faeces collected from different poultry farms in Lebanon. Broth microdilution (BMD) assay was performed to determine the antimicrobial resistance profiles. WGS was used to identify the genetic determinants behind the resistance in these isolates.<h4>Results</h4>BMD results showed that all of the 18 isolates were colistin resistant. Furthermore, resistance to trimethoprim/sulfamethoxazole was the most recorded among the isolates and only one isolate was resistant to cefepime."],"journal":["JAC-antimicrobial resistance"],"pagination":["dlab198"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8826752"],"repository":["biostudies-literature"],"pubmed_title":["Acquired resistome and plasmid sequencing of <i>mcr</i>-<i>1</i> carrying MDR Enterobacteriaceae from poultry and their relationship to STs associated with humans."],"pmcid":["PMC8826752"],"pubmed_authors":["Sleiman A","Doumith M","Matar GM","Alghoribi MF","Abou Fayad A","Okdah L","Kassem II","El Azzi M","Bawazeer RA"],"additional_accession":[]},"is_claimable":false,"name":"Acquired resistome and plasmid sequencing of <i>mcr</i>-<i>1</i> carrying MDR Enterobacteriaceae from poultry and their relationship to STs associated with humans.","description":"<h4>Objectives</h4>To investigate the acquired resistome in 18 colistin-resistant <i>Escherichia coli</i> isolated from different poultry farms in Lebanon, analyse Inc plasmids associated with <i>mcr</i> and assess potential transmission to humans.<h4>Methods</h4>A total of 18 <i>E. coli</i> were recovered from poultry faeces collected from different poultry farms in Lebanon. Broth microdilution (BMD) assay was performed to determine the antimicrobial resistance profiles. WGS was used to identify the genetic determinants behind the resistance in these isolates.<h4>Results</h4>BMD results showed that all of the 18 isolates were colistin resistant. Furthermore, resistance to trimethoprim/sulfamethoxazole was the most recorded among the isolates and only one isolate was resistant to cefepime.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2026-05-30T15:15:21.485Z","creation":"2025-04-19T22:40:03.219Z"},"accession":"S-EPMC8826752","cross_references":{"pubmed":["35156029"],"doi":["10.1093/jacamr/dlab198"]}}