{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["23(3)"],"submitter":["Demirjian C"],"pubmed_abstract":["Ralstonia solanacearum gram-negative phytopathogenic bacterium exerts its virulence through a type III secretion system (T3SS) that translocates type III effectors (T3Es) directly into the host cells. T3E secretion is finely controlled at the posttranslational level by helper proteins, T3SS control proteins, and type III chaperones. The HpaP protein, one of the type III secretion substrate specificity switch (T3S4) proteins, was previously highlighted as a virulence factor on Arabidopsis thaliana Col-0 accession. In this study, we set up a genome-wide association analysis to explore the natural diversity of response to the hpaP mutant of two A. thaliana mapping populations: a worldwide collection and a local population. Quantitative genetic variation revealed different genetic architecture"],"journal":["Molecular plant pathology"],"pagination":["321-338"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8828461"],"repository":["biostudies-literature"],"pubmed_title":["Study of natural diversity in response to a key pathogenicity regulator of Ralstonia solanacearum reveals new susceptibility genes in Arabidopsis thaliana."],"pmcid":["PMC8828461"],"pubmed_authors":["Demirjian C","Roux F","Berthome R","Desaint H","Genin S","Razavi N","Lonjon F","Vailleau F"],"additional_accession":[]},"is_claimable":false,"name":"Study of natural diversity in response to a key pathogenicity regulator of Ralstonia solanacearum reveals new susceptibility genes in Arabidopsis thaliana.","description":"Ralstonia solanacearum gram-negative phytopathogenic bacterium exerts its virulence through a type III secretion system (T3SS) that translocates type III effectors (T3Es) directly into the host cells. T3E secretion is finely controlled at the posttranslational level by helper proteins, T3SS control proteins, and type III chaperones. The HpaP protein, one of the type III secretion substrate specificity switch (T3S4) proteins, was previously highlighted as a virulence factor on Arabidopsis thaliana Col-0 accession. In this study, we set up a genome-wide association analysis to explore the natural diversity of response to the hpaP mutant of two A. thaliana mapping populations: a worldwide collection and a local population. Quantitative genetic variation revealed different genetic architecture","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-09-01T03:13:14.51Z","creation":"2025-04-25T17:38:22.183Z"},"accession":"S-EPMC8828461","cross_references":{"pubmed":["34939305"],"doi":["10.1111/mpp.13135"]}}