biostudies-literatureUnknown8Lin Z<h4>Purpose</h4>To investigate the imaging biomarkers of spectral-domain optical coherence tomography (SD-OCT) and their correlations with age and best-corrected visual acuity (BCVA) in patients with X-linked retinoschisis (XLRS).<h4>Methods</h4>OCT images of 72 eyes of 39 patients with confirmed XLRS were obtained to assess imaging biomarkers, including but not limited to the automatic evaluation of foveal thickness, central subfield thickness (CST), macular volume, and the manual measurement of area of macular schisis cavity (AMS). Correlations between age/BCVA and all OCT parameters were computed as well.<h4>Results</h4>In this study, median age was 10.5 (8-12) years old and median BCVA was 0.90 (0.70-1.00) logarithm of the minimum angle of resolution. Macular retinoschisis was found inFrontiers in medicine734888https://www.ebi.ac.uk/biostudies/studies/S-EPMC8828641biostudies-literatureInvestigation of Correlations Between Optical Coherence Tomography Biomarkers and Visual Acuity in X-Linked Retinoschisis.PMC8828641Hu YXiao YMaman Lawali DJAZeng XLin ZZang SYu HfalseInvestigation of Correlations Between Optical Coherence Tomography Biomarkers and Visual Acuity in X-Linked Retinoschisis.<h4>Purpose</h4>To investigate the imaging biomarkers of spectral-domain optical coherence tomography (SD-OCT) and their correlations with age and best-corrected visual acuity (BCVA) in patients with X-linked retinoschisis (XLRS).<h4>Methods</h4>OCT images of 72 eyes of 39 patients with confirmed XLRS were obtained to assess imaging biomarkers, including but not limited to the automatic evaluation of foveal thickness, central subfield thickness (CST), macular volume, and the manual measurement of area of macular schisis cavity (AMS). Correlations between age/BCVA and all OCT parameters were computed as well.<h4>Results</h4>In this study, median age was 10.5 (8-12) years old and median BCVA was 0.90 (0.70-1.00) logarithm of the minimum angle of resolution. Macular retinoschisis was found in2021-01-01T00:00:00Z20212025-04-04T12:43:45.483Z2025-04-04T12:43:45.483ZS-EPMC88286413515545910.3389/fmed.2021.734888