{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pankhurst T"],"funding":["Health Data Research UK","Medical Research Council","British Lung Foundation","Wellcome Trust","Academy of Medical Sciences"],"pagination":["e054027"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8830252"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(2)"],"pubmed_abstract":["<h4>Objective</h4>Use of National Early Warning Score 2 (NEWS2) has been mandated in adults admitted to acute hospitals in England. Urgent clinical review is recommended at NEWS2 ≥5. This policy is recognised as requiring ongoing evaluation. We assessed NEWS2 acquisition, alerting at key thresholds and patient outcomes, to understand how response recommendations would affect clinical resource allocation.<h4>Setting</h4>Adult acute hospital in England.<h4>Design</h4>Retrospective observational cohort study.<h4>Participants</h4>100 362 consecutive admissions between November 2018 and July 2019.<h4>Outcome</h4>Death or admission to intensive care unit within 24 hours of a score.<h4>Methods</h4>NEWS2 were assembled as single scores from consecutive 24-hour time frames, (the first NEWS2 termed "],"journal":["BMJ open"],"pubmed_title":["Evaluation of NEWS2 response thresholds in a retrospective observational study from a UK acute hospital."],"pmcid":["PMC8830252"],"funding_grant_id":["AMS-SGCL5-Sapey","HDR-9001","HDR-3006","LT12-8","MR/L008335/1","PIONEER 2019","HDR-3003","HDR-9002"],"pubmed_authors":["Pankhurst T","Evison F","Gyves H","Ball S","Sapey E","Gallier S","Gkoutos G"],"additional_accession":[]},"is_claimable":false,"name":"Evaluation of NEWS2 response thresholds in a retrospective observational study from a UK acute hospital.","description":"<h4>Objective</h4>Use of National Early Warning Score 2 (NEWS2) has been mandated in adults admitted to acute hospitals in England. Urgent clinical review is recommended at NEWS2 ≥5. This policy is recognised as requiring ongoing evaluation. We assessed NEWS2 acquisition, alerting at key thresholds and patient outcomes, to understand how response recommendations would affect clinical resource allocation.<h4>Setting</h4>Adult acute hospital in England.<h4>Design</h4>Retrospective observational cohort study.<h4>Participants</h4>100 362 consecutive admissions between November 2018 and July 2019.<h4>Outcome</h4>Death or admission to intensive care unit within 24 hours of a score.<h4>Methods</h4>NEWS2 were assembled as single scores from consecutive 24-hour time frames, (the first NEWS2 termed ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2025-04-21T15:40:48.959Z","creation":"2025-04-21T15:40:48.959Z"},"accession":"S-EPMC8830252","cross_references":{"pubmed":["35135770"],"doi":["10.1136/bmjopen-2021-054027"]}}