biostudies-literatureUnknown23(3)Krebs JIn this review, I summarize the present knowledge of the structural and functional properties of the mammalian plasma membrane calcium pump (PMCA). It is outlined how the cellular expression of the different spliced isoforms of the four genes are regulated under normal and pathological conditions.International journal of molecular sciences1027https://www.ebi.ac.uk/biostudies/studies/S-EPMC8835232biostudies-literatureStructure, Function and Regulation of the Plasma Membrane Calcium Pump in Health and Disease.PMC8835232Krebs JfalseStructure, Function and Regulation of the Plasma Membrane Calcium Pump in Health and Disease.In this review, I summarize the present knowledge of the structural and functional properties of the mammalian plasma membrane calcium pump (PMCA). It is outlined how the cellular expression of the different spliced isoforms of the four genes are regulated under normal and pathological conditions.2022-01-01T00:00:00Z2022 Jan2025-05-18T12:35:59.313Z2025-04-06T12:02:01.024ZS-EPMC88352323516294810.3390/ijms23031027