{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hood RB"],"funding":["NIEHS NIH HHS"],"pagination":["e191"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8835541"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["6(1)"],"pubmed_abstract":["<h4>Background</h4>Both acute and chronic exposure to fine particulate matter (PM<sub>2.5</sub>) have been linked to negative health outcomes. Studies have used metabolomics to describe the biological pathways linking PM<sub>2.5</sub> with disease but have focused on a single exposure window. We compared alterations in the serum metabolome following various short- and long-term PM<sub>2.5</sub> exposures.<h4>Methods</h4>Participants were women undergoing <i>in vitro</i> fertilization at a New England fertility clinic (n = 200). Women provided their residential address and provided a blood sample during controlled ovarian stimulation. PM<sub>2.5</sub> exposure was estimated in the 1, 2, and 3 days, 2 weeks, and 3 months prior to blood collection using a validated spatiotemporal model. We ut"],"journal":["Environmental epidemiology (Philadelphia, Pa.)"],"pubmed_title":["Length of PM<sub>2.5</sub> exposure and alterations in the serum metabolome among women undergoing infertility treatment."],"pmcid":["PMC8835541"],"funding_grant_id":["P30 ES000002","R01 ES009718","R00 ES026648","R01 ES022955","P30 ES019776"],"pubmed_authors":["Hood RB","Liang D","Tang Z","Kloog I","Gaskins AJ","Schwartz J","Laden F","Jones D"],"additional_accession":[]},"is_claimable":false,"name":"Length of PM<sub>2.5</sub> exposure and alterations in the serum metabolome among women undergoing infertility treatment.","description":"<h4>Background</h4>Both acute and chronic exposure to fine particulate matter (PM<sub>2.5</sub>) have been linked to negative health outcomes. Studies have used metabolomics to describe the biological pathways linking PM<sub>2.5</sub> with disease but have focused on a single exposure window. We compared alterations in the serum metabolome following various short- and long-term PM<sub>2.5</sub> exposures.<h4>Methods</h4>Participants were women undergoing <i>in vitro</i> fertilization at a New England fertility clinic (n = 200). Women provided their residential address and provided a blood sample during controlled ovarian stimulation. PM<sub>2.5</sub> exposure was estimated in the 1, 2, and 3 days, 2 weeks, and 3 months prior to blood collection using a validated spatiotemporal model. We ut","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2025-04-04T20:23:39.232Z","creation":"2025-04-04T20:23:39.232Z"},"accession":"S-EPMC8835541","cross_references":{"pubmed":["35169669"],"doi":["10.1097/EE9.0000000000000191"]}}