biostudies-literatureRocher FFrance GénomiqueAgence Nationale de la RechercheRegion Auvergne-Rhône-Alpes1914https://www.ebi.ac.uk/biostudies/studies/S-EPMC8836836biostudies-literatureUnknown23(3)<i>Fusarium graminearum</i>, the main causal agent of Fusarium Head Blight (FHB), is one of the most damaging pathogens in wheat. Because of the complex organization of wheat resistance to FHB, this pathosystem represents a relevant model to elucidate the molecular mechanisms underlying plant susceptibility and to identify their main drivers, the pathogen's effectors. Although the <i>F. graminearum</i> catalog of effectors has been well characterized at the genome scale, in planta studies are needed to confirm their effective accumulation in host tissues and to identify their role during the infection process. Taking advantage of the genetic variability from both species, a RNAseq-based profiling of gene expression was performed during an infection time course using an aggressive <i>F. graInternational journal of molecular sciences<i>Fusarium graminearum</i> Infection Strategy in Wheat Involves a Highly Conserved Genetic Program That Controls the Expression of a Core Effectome.PMC8836836ANR-17-EUR-0007WheatOMICSANR-15-CE21-001016-IDEX-0001 CAP 20-25FEDERLabel PLangin TPhilippe GBonhomme LRocher FMartin MLAlouane Tfalse<i>Fusarium graminearum</i> Infection Strategy in Wheat Involves a Highly Conserved Genetic Program That Controls the Expression of a Core Effectome.<i>Fusarium graminearum</i>, the main causal agent of Fusarium Head Blight (FHB), is one of the most damaging pathogens in wheat. Because of the complex organization of wheat resistance to FHB, this pathosystem represents a relevant model to elucidate the molecular mechanisms underlying plant susceptibility and to identify their main drivers, the pathogen's effectors. Although the <i>F. graminearum</i> catalog of effectors has been well characterized at the genome scale, in planta studies are needed to confirm their effective accumulation in host tissues and to identify their role during the infection process. Taking advantage of the genetic variability from both species, a RNAseq-based profiling of gene expression was performed during an infection time course using an aggressive <i>F. gra2022-01-01T00:00:00Z2022 Feb2026-04-08T17:37:34.426Z2025-04-06T12:01:57.465ZS-EPMC88368363516383410.3390/ijms23031914