{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wu H"],"funding":["Self-Planned Task of State Key Laboratory of Robotics and System"],"pagination":["418"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8840109"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(3)"],"pubmed_abstract":["Adsorption of urea from dialysate is essential for wearable artificial kidneys (WRK). Molecularly imprinted microspheres with nanoporous and multilayered structures are prepared based on liquid-liquid phase separation (LLPS), which can selectively adsorb urea. In addition, we combine the microspheres with a designed polydimethylsiloxane (PDMS) chip to propose an efficient urea adsorption platform. In this work, we propose a formulation of LLPS including Tripropylene glycol diacrylate (TPGDA), ethanol, and acrylic acid (30% v/v), to prepare urea molecularly imprinted microspheres in a simple and highly controllable method. These microspheres have urea molecular imprinting sites on the surface and inside, allowing selective adsorption of urea and preservation of other essential constituents."],"journal":["Nanomaterials (Basel, Switzerland)"],"pubmed_title":["Controllable Fabrication of Molecularly Imprinted Microspheres with Nanoporous and Multilayered Structure for Dialysate Regeneration."],"pmcid":["PMC8840109"],"funding_grant_id":["SKLRS201803B"],"pubmed_authors":["Liu L","Xue C","Ren Y","Jiang H","Chen X","Zhang S","Wu W","Wu H"],"additional_accession":[]},"is_claimable":false,"name":"Controllable Fabrication of Molecularly Imprinted Microspheres with Nanoporous and Multilayered Structure for Dialysate Regeneration.","description":"Adsorption of urea from dialysate is essential for wearable artificial kidneys (WRK). Molecularly imprinted microspheres with nanoporous and multilayered structures are prepared based on liquid-liquid phase separation (LLPS), which can selectively adsorb urea. In addition, we combine the microspheres with a designed polydimethylsiloxane (PDMS) chip to propose an efficient urea adsorption platform. In this work, we propose a formulation of LLPS including Tripropylene glycol diacrylate (TPGDA), ethanol, and acrylic acid (30% v/v), to prepare urea molecularly imprinted microspheres in a simple and highly controllable method. These microspheres have urea molecular imprinting sites on the surface and inside, allowing selective adsorption of urea and preservation of other essential constituents.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-26T03:57:23.935Z","creation":"2025-04-06T10:58:02.197Z"},"accession":"S-EPMC8840109","cross_references":{"pubmed":["35159766"],"doi":["10.3390/nano12030418"]}}