{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Huang Z"],"funding":["Ministry of Education - Singapore"],"pagination":["107919"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8844217"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["41"],"pubmed_abstract":["We present four datasets on proteomics profiling of HeLa and SiHa cell lines associated with the research described in the paper \"PROTREC: A probability-based approach for recovering missing proteins based on biological networks\" [1]. Proteins in each cell line were acquired by two different data acquisition methods. The first was Data Dependent Acquisition-Parallel Accumulation Serial Fragmentation (DDA-PASEF) and the second was Parallel Accumulation-Serial Fragmentation combined with data-independent acquisition (diaPASEF) [2], [3]. Protein assembly was performed following search against the Swiss-Prot Human database using Peaks Studio for DDA datasets and Spectronaut for DIA datasets. The assembled result contains identified PSMs, peptides and proteins that are above threshold for each "],"journal":["Data in brief"],"pubmed_title":["Proteomic datasets of HeLa and SiHa cell lines acquired by DDA-PASEF and diaPASEF."],"pmcid":["PMC8844217"],"funding_grant_id":["RG35/20"],"pubmed_authors":["Liu X","Wong BJ","Huang Z","Wong L","Du X","Guo T","Gao H","Kong W","Goh WWB"],"additional_accession":[]},"is_claimable":false,"name":"Proteomic datasets of HeLa and SiHa cell lines acquired by DDA-PASEF and diaPASEF.","description":"We present four datasets on proteomics profiling of HeLa and SiHa cell lines associated with the research described in the paper \"PROTREC: A probability-based approach for recovering missing proteins based on biological networks\" [1]. Proteins in each cell line were acquired by two different data acquisition methods. The first was Data Dependent Acquisition-Parallel Accumulation Serial Fragmentation (DDA-PASEF) and the second was Parallel Accumulation-Serial Fragmentation combined with data-independent acquisition (diaPASEF) [2], [3]. Protein assembly was performed following search against the Swiss-Prot Human database using Peaks Studio for DDA datasets and Spectronaut for DIA datasets. The assembled result contains identified PSMs, peptides and proteins that are above threshold for each ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-21T17:06:10.182Z","creation":"2025-04-21T17:06:10.182Z"},"accession":"S-EPMC8844217","cross_references":{"pubmed":["35198691"],"doi":["10.1016/j.dib.2022.107919"]}}