{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bizot E"],"funding":["Fondation ARC pour la Recherche sur le Cancer","Fondation pour la recherche médicale FRM"],"pagination":["e0194921"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8846429"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["66(2)"],"pubmed_abstract":["We described and characterized Shiga-toxin-producing Escherichia coli (STEC) strains with high levels of resistance to azithromycin isolated in France between 2004 and 2020. Nine of 1,715 (0.52%) STEC strains were resistant to azithromycin, with an increase since 2017. One isolate carried a plasmid-borne <i>mef</i>(C)-<i>mph</i>(G) gene combination, described here for the first time for E. coli. Azithromycin resistance, although rare, needs consideration, as this treatment may be useful in cases of STEC infection."],"journal":["Antimicrobial agents and chemotherapy"],"pubmed_title":["Azithromycin Resistance in Shiga Toxin-Producing Escherichia coli in France between 2004 and 2020 and Detection of <i>mef</i>(C)-<i>mph</i>(G) Genes."],"pmcid":["PMC8846429"],"funding_grant_id":["DOC20190509066","EQU201903007848"],"pubmed_authors":["Magnan M","Birgy A","Camelena F","Bidet P","Liguori S","Bercot B","Bizot E","Cointe A","Mariani-Kurkdjian P","Lefevre S","Hobson CA","Bonacorsi S","Merimeche M","Courroux C","Weill FX","Bridier-Nahmias A"],"additional_accession":[]},"is_claimable":false,"name":"Azithromycin Resistance in Shiga Toxin-Producing Escherichia coli in France between 2004 and 2020 and Detection of <i>mef</i>(C)-<i>mph</i>(G) Genes.","description":"We described and characterized Shiga-toxin-producing Escherichia coli (STEC) strains with high levels of resistance to azithromycin isolated in France between 2004 and 2020. Nine of 1,715 (0.52%) STEC strains were resistant to azithromycin, with an increase since 2017. One isolate carried a plasmid-borne <i>mef</i>(C)-<i>mph</i>(G) gene combination, described here for the first time for E. coli. Azithromycin resistance, although rare, needs consideration, as this treatment may be useful in cases of STEC infection.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2025-04-04T13:25:50.634Z","creation":"2024-11-19T16:34:40.08Z"},"accession":"S-EPMC8846429","cross_references":{"pubmed":["34871091"],"doi":["10.1128/AAC.01949-21","10.1128/aac.01949-21"]}}