biostudies-literatureSaldich EBNIAAA NIH HHS1131-1142https://www.ebi.ac.uk/biostudies/studies/S-EPMC8848829biostudies-literatureUnknown40(7)<h4>Introduction</h4>Wearable devices that obtain transdermal alcohol concentration (TAC) could become valuable research tools for monitoring alcohol consumption levels in naturalistic environments if the TAC they produce could be converted into quantitatively-meaningful estimates of breath alcohol concentration (eBrAC). Our team has developed mathematical models to produce eBrAC from TAC, but it is not yet clear how a variety of factors affect the accuracy of the models. Stomach content is one factor that is known to affect breath alcohol concentration (BrAC), but its effect on the BrAC-TAC relationship has not yet been studied.<h4>Methods</h4>We examine the BrAC-TAC relationship by having two investigators participate in four laboratory drinking sessions with varied stomach content condiDrug and alcohol reviewEffects of stomach content on the breath alcohol concentration-transdermal alcohol concentration relationship.PMC8848829R01 AA026368Bartroff JLuczak SEWang CRosen IGSaldich EBfalseEffects of stomach content on the breath alcohol concentration-transdermal alcohol concentration relationship.<h4>Introduction</h4>Wearable devices that obtain transdermal alcohol concentration (TAC) could become valuable research tools for monitoring alcohol consumption levels in naturalistic environments if the TAC they produce could be converted into quantitatively-meaningful estimates of breath alcohol concentration (eBrAC). Our team has developed mathematical models to produce eBrAC from TAC, but it is not yet clear how a variety of factors affect the accuracy of the models. Stomach content is one factor that is known to affect breath alcohol concentration (BrAC), but its effect on the BrAC-TAC relationship has not yet been studied.<h4>Methods</h4>We examine the BrAC-TAC relationship by having two investigators participate in four laboratory drinking sessions with varied stomach content condi2021-01-01T00:00:00Z2021 Nov2025-04-19T04:19:08.845Z2025-04-19T04:19:08.845ZS-EPMC88488293371303710.1111/dar.13267