{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Liu FA"],"funding":["National Institute of Mental Health","Division of Industrial Innovation and Partnerships"],"pagination":["017512"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8856629"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["169"],"pubmed_abstract":["Carbon fiber microelectrodes (CFMEs) have been used to detect neurotransmitters and other biomolecules using fast-scan cyclic voltammetry (FSCV) for the past few decades. This technique measures neurotransmitters such as dopamine and, more recently, physiologically relevant neuropeptides. Oxytocin, a pleiotropic peptide hormone, is physiologically important for adaptation, development, reproduction, and social behavior. This neuropeptide functions as a stress-coping molecule, an anti-inflammatory agent, and serves as an antioxidant with protective effects especially during adversity or trauma. Here, we measure tyrosine using the Modified Sawhorse Waveform (MSW), enabling enhanced electrode sensitivity for the amino acid and oxytocin peptide. Applying the MSW, decreased surface fouling and "],"journal":["Journal of the Electrochemical Society"],"pubmed_title":["Modified Sawhorse Waveform for the Voltammetric Detection of Oxytocin."],"pmcid":["PMC8856629"],"funding_grant_id":["NIH 1R41NS113702-01","NSF I-Corps #1936173"],"pubmed_authors":["Hartings MR","Zestos AG","Ardabili N","Brown I","Zou S","Nikopoulou R","Liu FA","Rafi H","Lopez A","Cook C"],"additional_accession":[]},"is_claimable":false,"name":"Modified Sawhorse Waveform for the Voltammetric Detection of Oxytocin.","description":"Carbon fiber microelectrodes (CFMEs) have been used to detect neurotransmitters and other biomolecules using fast-scan cyclic voltammetry (FSCV) for the past few decades. This technique measures neurotransmitters such as dopamine and, more recently, physiologically relevant neuropeptides. Oxytocin, a pleiotropic peptide hormone, is physiologically important for adaptation, development, reproduction, and social behavior. This neuropeptide functions as a stress-coping molecule, an anti-inflammatory agent, and serves as an antioxidant with protective effects especially during adversity or trauma. Here, we measure tyrosine using the Modified Sawhorse Waveform (MSW), enabling enhanced electrode sensitivity for the amino acid and oxytocin peptide. Applying the MSW, decreased surface fouling and ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-21T15:21:40.755Z","creation":"2025-04-21T15:21:40.755Z"},"accession":"S-EPMC8856629","cross_references":{"pubmed":["35185166"],"doi":["10.1149/1945-7111/ac4aae"]}}