biostudies-literatureUnknown28(6)Akashi Y<h4>Introduction</h4>The diagnostic accuracy of antigen testing of anterior nasal (AN) samples for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has not been evaluated in the Japanese population. This study assessed the diagnostic accuracy of the Roche SARS-CoV-2 rapid antigen test (rapid antigen test) using AN samples.<h4>Methods</h4>Two AN samples and one nasopharyngeal (NP) sample were collected from individuals undergoing screening for SARS-CoV-2 infection. The results of the rapid antigen test and the reverse-transcription polymerase chain reaction (RT-PCR) test using AN samples were compared to those of RT-PCR tests using NP samples.<h4>Results</h4>Samples were collected from 800 participants, 95 and 110 of whom tested positive for SARS-CoV-2 on RT-PCR teJournal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy780-785https://www.ebi.ac.uk/biostudies/studies/S-EPMC8866084biostudies-literatureA prospective clinical evaluation of the diagnostic accuracy of the SARS-CoV-2 rapid antigen test using anterior nasal samples.PMC8866084Notake SKurihara YAkashi YUeda ANakamura KHorie MTakeuchi YAdachi YKiyasu YTerada NTogashi KSuzuki HfalseA prospective clinical evaluation of the diagnostic accuracy of the SARS-CoV-2 rapid antigen test using anterior nasal samples.<h4>Introduction</h4>The diagnostic accuracy of antigen testing of anterior nasal (AN) samples for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has not been evaluated in the Japanese population. This study assessed the diagnostic accuracy of the Roche SARS-CoV-2 rapid antigen test (rapid antigen test) using AN samples.<h4>Methods</h4>Two AN samples and one nasopharyngeal (NP) sample were collected from individuals undergoing screening for SARS-CoV-2 infection. The results of the rapid antigen test and the reverse-transcription polymerase chain reaction (RT-PCR) test using AN samples were compared to those of RT-PCR tests using NP samples.<h4>Results</h4>Samples were collected from 800 participants, 95 and 110 of whom tested positive for SARS-CoV-2 on RT-PCR te2022-01-01T00:00:00Z2022 Jun2026-03-18T13:18:34.794Z2025-04-06T21:52:03.776ZS-EPMC88660843525626810.1016/j.jiac.2022.02.016