{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(2)"],"submitter":["Agirbasli D"],"pubmed_abstract":["Vitamin D deficiency is common among postmenopausal women. Telomere length can be a potential protective mechanism for age-related diseases. The objective of our study is to examine the association of vitamin D supplementation on leukocyte telomere length (LTL) in healthy postmenopausal women with vitamin D deficiency. The study was designed as a placebo-controlled study to investigate the short-term effects of vitamin D supplementation and seasonal changes on vitamin D related parameters, including 25(OH)D, 1,25(OH)2D parathormone (PTH), Vitamin D binding protein (VDBP), vitamin D receptor (VDR), and telomere length in a cohort of postmenopausal women (n = 102). The group was divided as supplementation (n = 52) and placebo groups (n = 50). All parameters were measured before and after tre"],"journal":["PloS one"],"pagination":["e0264337"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8870535"],"repository":["biostudies-literature"],"pubmed_title":["Leukocyte telomere length as a compensatory mechanism in vitamin D metabolism."],"pmcid":["PMC8870535"],"pubmed_authors":["Aksungar FB","Agirbasli D","Muftuoglu M","Kalyoncu M","Agirbasli M"],"additional_accession":[]},"is_claimable":false,"name":"Leukocyte telomere length as a compensatory mechanism in vitamin D metabolism.","description":"Vitamin D deficiency is common among postmenopausal women. Telomere length can be a potential protective mechanism for age-related diseases. The objective of our study is to examine the association of vitamin D supplementation on leukocyte telomere length (LTL) in healthy postmenopausal women with vitamin D deficiency. The study was designed as a placebo-controlled study to investigate the short-term effects of vitamin D supplementation and seasonal changes on vitamin D related parameters, including 25(OH)D, 1,25(OH)2D parathormone (PTH), Vitamin D binding protein (VDBP), vitamin D receptor (VDR), and telomere length in a cohort of postmenopausal women (n = 102). The group was divided as supplementation (n = 52) and placebo groups (n = 50). All parameters were measured before and after tre","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-21T23:11:01.928Z","creation":"2025-04-05T19:06:43.074Z"},"accession":"S-EPMC8870535","cross_references":{"pubmed":["35202418"],"doi":["10.1371/journal.pone.0264337"]}}