{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["19(3)"],"submitter":["Manning L"],"funding":["The Western Australia Department of Health"],"pubmed_abstract":["There is an urgent need for interventions that improve healing time, prevent amputations and recurrent ulceration in patients with diabetes-related foot wounds. In this randomised, open-label trial, participants were randomised to receive an application of non-cultured autologous skin cells (\"spray-on\" skin; ReCell) or standard care interventions for large (>6 cm<sup>2</sup> ), adequately vascularised wounds. The primary outcome was complete healing at 6 months, determined by assessors blinded to the intervention. Forty-nine eligible foot wounds in 45 participants were randomised. An evaluable primary outcome was available for all wounds. The median (interquartile range) wound area at baseline was 11.4 (8.8-17.6) cm<sup>2</sup> . A total of 32 (65.3%) index wounds were completely healed at"],"journal":["International wound journal"],"pagination":["470-481"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8874115"],"repository":["biostudies-literature"],"pubmed_title":["Wound healing with \"spray-on\" autologous skin grafting (ReCell) compared with standard care in patients with large diabetes-related foot wounds: an open-label randomised controlled trial."],"pmcid":["PMC8874115"],"pubmed_authors":["Norman PE","Davis WA","Hiew J","Baba M","Hamilton EJ","Ferreira IB","Carville K","Gittings P","Wood F","Raby E","Ritter JC","Ryan E","Manning L"],"additional_accession":[]},"is_claimable":false,"name":"Wound healing with \"spray-on\" autologous skin grafting (ReCell) compared with standard care in patients with large diabetes-related foot wounds: an open-label randomised controlled trial.","description":"There is an urgent need for interventions that improve healing time, prevent amputations and recurrent ulceration in patients with diabetes-related foot wounds. In this randomised, open-label trial, participants were randomised to receive an application of non-cultured autologous skin cells (\"spray-on\" skin; ReCell) or standard care interventions for large (>6 cm<sup>2</sup> ), adequately vascularised wounds. The primary outcome was complete healing at 6 months, determined by assessors blinded to the intervention. Forty-nine eligible foot wounds in 45 participants were randomised. An evaluable primary outcome was available for all wounds. The median (interquartile range) wound area at baseline was 11.4 (8.8-17.6) cm<sup>2</sup> . A total of 32 (65.3%) index wounds were completely healed at","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-04-04T12:43:38.536Z","creation":"2025-04-04T12:43:38.536Z"},"accession":"S-EPMC8874115","cross_references":{"pubmed":["34156758"],"doi":["10.1111/iwj.13646"]}}