{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Li B"],"pubmed_abstract":["<h4>Objective</h4>This study was designed to evaluate the operability, effectiveness, and safety of the automated titanium suture fastener in a preclinical ovine model in comparison with manual tying in a mitral valve annuloplasty ring implantation surgery.<h4>Methods</h4>Eighteen adult Small-tailed Han sheep were prepared for the surgery of mitral valve annuloplasty ring implantation through lateral thoracotomy under cardiopulmonary bypass (CBP). A total of 12 stitches were performed to secure an annuloplasty ring, with 6 stitches done with the automated fastener and the other 6 by manual tying. The knotting time for the automated fastener or manual tying was recorded, respectively. The firmness of knots, mitral valve integrity, biocompatibility, thrombosis, local reactions, and other asp"],"journal":["Frontiers in cardiovascular medicine"],"pagination":["783208"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8874148"],"repository":["biostudies-literature"],"pubmed_title":["Safety and Effectiveness Outcomes of a Novel Automated Titanium Suture Fastener Device Applied for Heart Valve Surgery in an Ovine Model."],"pmcid":["PMC8874148"],"pubmed_authors":["Bai S","Zhu J","Luo J","Zhang M","Yang B","Li B","Zhang L","Wang X","Yue G","Sun Y"],"additional_accession":[]},"is_claimable":false,"name":"Safety and Effectiveness Outcomes of a Novel Automated Titanium Suture Fastener Device Applied for Heart Valve Surgery in an Ovine Model.","description":"<h4>Objective</h4>This study was designed to evaluate the operability, effectiveness, and safety of the automated titanium suture fastener in a preclinical ovine model in comparison with manual tying in a mitral valve annuloplasty ring implantation surgery.<h4>Methods</h4>Eighteen adult Small-tailed Han sheep were prepared for the surgery of mitral valve annuloplasty ring implantation through lateral thoracotomy under cardiopulmonary bypass (CBP). A total of 12 stitches were performed to secure an annuloplasty ring, with 6 stitches done with the automated fastener and the other 6 by manual tying. The knotting time for the automated fastener or manual tying was recorded, respectively. The firmness of knots, mitral valve integrity, biocompatibility, thrombosis, local reactions, and other asp","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-25T17:37:47.739Z","creation":"2025-04-25T17:37:47.739Z"},"accession":"S-EPMC8874148","cross_references":{"pubmed":["35224036"],"doi":["10.3389/fcvm.2022.783208"]}}