biostudies-literatureUnknown11(4)Rostamzad PThe aim of this study was to describe the ophthalmic abnormalities and their prevalence in craniosynostosis prior to craniofacial surgery. A systematic search was conducted on Medline OVID, Embase, Cochrane, Google Scholar, Web of Science Core Collection. Inclusion criteria were English papers, children aged <18 years with non-syndromic and syndromic craniosynostosis, case reports, case series, and case-control studies. A system of domains was established consisting of an anatomic and functional ophthalmic domain. A meta-analysis of single proportions was carried out using random effects model and pooled mean proportions with 95% confidence intervals (CI) were calculated. Thirty-two papers analyzing 2027 patients were included. Strabismus was the most common anomaly in non-syndromic cranioJournal of clinical medicine1060https://www.ebi.ac.uk/biostudies/studies/S-EPMC8877705biostudies-literaturePrevalence of Ocular Anomalies in Craniosynostosis: A Systematic Review and Meta-Analysis.PMC8877705Versnel SLArslan ZFRostamzad PPleumeekers MMMathijssen IMJKoudstaal MJLoudon SEfalsePrevalence of Ocular Anomalies in Craniosynostosis: A Systematic Review and Meta-Analysis.The aim of this study was to describe the ophthalmic abnormalities and their prevalence in craniosynostosis prior to craniofacial surgery. A systematic search was conducted on Medline OVID, Embase, Cochrane, Google Scholar, Web of Science Core Collection. Inclusion criteria were English papers, children aged <18 years with non-syndromic and syndromic craniosynostosis, case reports, case series, and case-control studies. A system of domains was established consisting of an anatomic and functional ophthalmic domain. A meta-analysis of single proportions was carried out using random effects model and pooled mean proportions with 95% confidence intervals (CI) were calculated. Thirty-two papers analyzing 2027 patients were included. Strabismus was the most common anomaly in non-syndromic cranio2022-01-01T00:00:00Z2022 Feb2025-04-04T08:57:34.039Z2024-11-09T10:31:54.862ZS-EPMC88777053520733210.3390/jcm11041060