biostudies-literatureUnknown101(8)Jefferys D<h4>Rationale</h4>Gallbladder cancer is the most common malignancy of the biliary tree. Despite this, the only curative therapy remains surgical resection of the lesion achieving microscopically clear margins before malignant spread has occurred. Gallbladder duplication is an uncommon anatomical variance which occurs globally. It can present in a range of ways dependent on the embryological origin of the variance.<h4>Case</h4>A 52-year-old female presented for planned laparoscopic cholecystectomy in the context of cholelithiasis resulting in recurrent biliary colic. The patient had no personal history of malignancy or significant medical comorbidities.<h4>Diagnosis</h4>Intraoperatively, the patient was found to have Y-insertion variation of gallbladder duplication. Histopathology of the reMedicinee28829https://www.ebi.ac.uk/biostudies/studies/S-EPMC8878699biostudies-literatureIncidental adenocarcinoma of the gallbladder in a patient with Y insertion gallbladder duplication in the context of recurrent biliary colic: A video case report.PMC8878699Jefferys DRoy SMajid AfalseIncidental adenocarcinoma of the gallbladder in a patient with Y insertion gallbladder duplication in the context of recurrent biliary colic: A video case report.<h4>Rationale</h4>Gallbladder cancer is the most common malignancy of the biliary tree. Despite this, the only curative therapy remains surgical resection of the lesion achieving microscopically clear margins before malignant spread has occurred. Gallbladder duplication is an uncommon anatomical variance which occurs globally. It can present in a range of ways dependent on the embryological origin of the variance.<h4>Case</h4>A 52-year-old female presented for planned laparoscopic cholecystectomy in the context of cholelithiasis resulting in recurrent biliary colic. The patient had no personal history of malignancy or significant medical comorbidities.<h4>Diagnosis</h4>Intraoperatively, the patient was found to have Y-insertion variation of gallbladder duplication. Histopathology of the re2022-01-01T00:00:00Z2022 Feb2025-05-18T12:07:52.057Z2025-05-18T12:07:52.057ZS-EPMC88786993521228010.1097/MD.0000000000028829