{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(2)"],"submitter":["Lozica L"],"pubmed_abstract":["<i>Escherichia coli</i> is the main bacterial cause of major economic losses and animal welfare issues in poultry production. In this study, we investigate the effect of an autogenous vaccine on <i>E. coli</i> strains longitudinally isolated from broiler breeder flocks on two farms. In total, 115 <i>E. coli</i> isolates were sequenced using Illumina technologies, and compared based on a single-nucleotide polymorphism (SNP) analysis of the core-genome and antimicrobial resistance (AMR) genes they carried. The results showed that SNP-based phylogeny corresponds to a previous multilocus-sequence typing (MLST)-based phylogeny. Highly virulent sequence types (STs), including ST117-F, ST95-B2, ST131-B2 and ST390-B2, showed a higher level of homogeneity. On the other hand, less frequent STs, such"],"journal":["Microorganisms"],"pagination":["377"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8879504"],"repository":["biostudies-literature"],"pubmed_title":["Genomic Analysis of <i>Escherichia coli</i> Longitudinally Isolated from Broiler Breeder Flocks after the Application of an Autogenous Vaccine."],"pmcid":["PMC8879504"],"pubmed_authors":["Li G","Villumsen KR","Gottstein Z","Hu X","Maljkovic MM","Lozica L"],"additional_accession":[]},"is_claimable":false,"name":"Genomic Analysis of <i>Escherichia coli</i> Longitudinally Isolated from Broiler Breeder Flocks after the Application of an Autogenous Vaccine.","description":"<i>Escherichia coli</i> is the main bacterial cause of major economic losses and animal welfare issues in poultry production. In this study, we investigate the effect of an autogenous vaccine on <i>E. coli</i> strains longitudinally isolated from broiler breeder flocks on two farms. In total, 115 <i>E. coli</i> isolates were sequenced using Illumina technologies, and compared based on a single-nucleotide polymorphism (SNP) analysis of the core-genome and antimicrobial resistance (AMR) genes they carried. The results showed that SNP-based phylogeny corresponds to a previous multilocus-sequence typing (MLST)-based phylogeny. Highly virulent sequence types (STs), including ST117-F, ST95-B2, ST131-B2 and ST390-B2, showed a higher level of homogeneity. On the other hand, less frequent STs, such","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2026-04-08T17:33:24.124Z","creation":"2025-04-04T10:01:53.846Z"},"accession":"S-EPMC8879504","cross_references":{"pubmed":["35208834"],"doi":["10.3390/microorganisms10020377"]}}