{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(2)"],"submitter":["Lee HJ"],"pubmed_abstract":["<h4>Background</h4>We aimed to clarify the sex differences in various cardiovascular and non-cardiovascular outcomes, and to investigate whether sex differences in outcomes are affected by age in hypertrophic cardiomyopathy (HCM).<h4>Methods</h4>A cohort of 835 patients with HCM initially evaluated during 2007-2019 were followed for a median of 6.4 years. Study outcomes were all-cause death, cardiovascular and non-cardiovascular death, sudden cardiac death (SCD)/SCD equivalent events, heart failure (HF) events, and the composite cardiovascular outcome including cardiovascular death, SCD/SCD equivalent events, admission for HF, and heart transplantation.<h4>Results</h4>Women were 5 years older (women 59.9±13.5 vs. men 54.9±11.4 years), had worse dyspnea, and greater left ventricular (LV) di"],"journal":["PloS one"],"pagination":["e0264580"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8880392"],"repository":["biostudies-literature"],"pubmed_title":["Age-related sex differences in the outcomes of patients with hypertrophic cardiomyopathy."],"pmcid":["PMC8880392"],"pubmed_authors":["Kim HK","Ommen SR","Chang SA","Choi YJ","Kim YJ","Lee SC","Lee HJ","Kim J","Park JB","Lee SP"],"additional_accession":[]},"is_claimable":false,"name":"Age-related sex differences in the outcomes of patients with hypertrophic cardiomyopathy.","description":"<h4>Background</h4>We aimed to clarify the sex differences in various cardiovascular and non-cardiovascular outcomes, and to investigate whether sex differences in outcomes are affected by age in hypertrophic cardiomyopathy (HCM).<h4>Methods</h4>A cohort of 835 patients with HCM initially evaluated during 2007-2019 were followed for a median of 6.4 years. Study outcomes were all-cause death, cardiovascular and non-cardiovascular death, sudden cardiac death (SCD)/SCD equivalent events, heart failure (HF) events, and the composite cardiovascular outcome including cardiovascular death, SCD/SCD equivalent events, admission for HF, and heart transplantation.<h4>Results</h4>Women were 5 years older (women 59.9±13.5 vs. men 54.9±11.4 years), had worse dyspnea, and greater left ventricular (LV) di","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T08:58:29.975Z","creation":"2025-04-04T08:58:29.975Z"},"accession":"S-EPMC8880392","cross_references":{"pubmed":["35213653"],"doi":["10.1371/journal.pone.0264580"]}}