biostudies-literatureHan BNational Natural Science Foundation of ChinaYouth Innovation Promotion Association of the Chinese Academy of Sciences57https://www.ebi.ac.uk/biostudies/studies/S-EPMC8886767biostudies-literatureUnknown20(1)<h4>Background</h4>Understanding the processes governing angiosperm seed growth and development is essential both for fundamental plant biology and for agronomic purposes. Master regulators of angiosperm seed development are expressed in a seed-specific manner. However, it is unclear how this seed specificity of transcription is established. In some vertebrates, DNA methylation valleys (DMVs) are highly conserved and strongly associated with key developmental genes, but comparable studies in plants are limited to Arabidopsis and soybean. Castor bean (Ricinus communis) is a valuable model system for the study of seed biology in dicots and source of economically important castor oil. Unlike other dicots such as Arabidopsis and soybean, castor bean seeds have a relatively large and persistentBMC biologyEpigenetic regulation of seed-specific gene expression by DNA methylation valleys in castor bean.PMC888676731661143002, 31970341 and 317718392020389Han BZhang YLi DZLiu AWu DXu WfalseEpigenetic regulation of seed-specific gene expression by DNA methylation valleys in castor bean.<h4>Background</h4>Understanding the processes governing angiosperm seed growth and development is essential both for fundamental plant biology and for agronomic purposes. Master regulators of angiosperm seed development are expressed in a seed-specific manner. However, it is unclear how this seed specificity of transcription is established. In some vertebrates, DNA methylation valleys (DMVs) are highly conserved and strongly associated with key developmental genes, but comparable studies in plants are limited to Arabidopsis and soybean. Castor bean (Ricinus communis) is a valuable model system for the study of seed biology in dicots and source of economically important castor oil. Unlike other dicots such as Arabidopsis and soybean, castor bean seeds have a relatively large and persistent2022-01-01T00:00:00Z2022 Mar2025-04-04T13:21:27.522Z2025-04-04T13:21:27.522ZS-EPMC88867673522726710.1186/s12915-022-01259-6