biostudies-literatureWang JBCancer Institute, Chinese Academy of Medical SciencesInternational Agency for Research on Cancer2983-2989https://www.ebi.ac.uk/biostudies/studies/S-EPMC8890481biostudies-literatureUnknown23(11)<h4>Background</h4>Most cancers are due to modifiable lifestyle and environmental risk factors, and are potentially preventable. No studies have provided a systematic quantitative assessment of the burden of cancer mortality and incidence attributable to known risk factors in China.<h4>Methods</h4>We calculated the proportions of cancer deaths and new cases attributable to known risk factors in China, based on the prevalence of exposure around 1990 and national data on cancer mortality and incidence for the year 2005.<h4>Results</h4>Chronic infection is the main risk factor for cancer in China, accounting for 29.4% of cancer deaths (31.7% in men and 25.3% in women), followed by tobacco smoking (22.6% with 32.7% in men and 5.0% in women), low fruit intake (13.0%), alcohol drinking (4.4%), lAnnals of oncology : official journal of the European Society for Medical OncologyAttributable causes of cancer in China.PMC8890481JK2011B19CRA No GEE/08/19Qiao YLShi JFFan YGWang DLi PJi JWei WQLi LJiang YWang JBLiang HChen WQXiao HJDeng SSBoffetta PXiang WfalseAttributable causes of cancer in China.<h4>Background</h4>Most cancers are due to modifiable lifestyle and environmental risk factors, and are potentially preventable. No studies have provided a systematic quantitative assessment of the burden of cancer mortality and incidence attributable to known risk factors in China.<h4>Methods</h4>We calculated the proportions of cancer deaths and new cases attributable to known risk factors in China, based on the prevalence of exposure around 1990 and national data on cancer mortality and incidence for the year 2005.<h4>Results</h4>Chronic infection is the main risk factor for cancer in China, accounting for 29.4% of cancer deaths (31.7% in men and 25.3% in women), followed by tobacco smoking (22.6% with 32.7% in men and 5.0% in women), low fruit intake (13.0%), alcohol drinking (4.4%), l2012-01-01T00:00:00Z2012 Nov2025-04-19T12:59:05.522Z2025-04-19T12:59:05.522ZS-EPMC88904812268917810.1093/annonc/mds139