{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Argento E"],"funding":["National Institute of Health and Medical Research","NIDA NIH HHS","St. Paul&apos;s Foundation","Michael Smith Foundation for Health Research","National Institutes of Health","National Institute on Drug Abuse","Canadian Institutes of Health Research","CIHR"],"pagination":["103518"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8890776"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["100"],"pubmed_abstract":["<h4>Background</h4>Research into the therapeutic and naturalistic uses of psychedelics for improving outcomes related to mental health disorders has generated increasing interest in recent years. While controlled clinical trials of psychedelics have signaled benefits for treating substance use disorders, this area has not been well studied in the context of naturalistic psychedelic use. This study sought to investigate the possible relationship between recent naturalistic psychedelic use and subsequent daily illicit opioid use among people who use drugs (PWUD).<h4>Methods</h4>Data (2006-2018) were drawn from three harmonized prospective cohorts of community-recruited PWUD in Vancouver, Canada. We used multivariable generalized linear mixed-effects modeling (GLMM) to estimate the independen"],"journal":["The International journal on drug policy"],"pubmed_title":["Psychedelic use is associated with reduced daily opioid use among people who use illicit drugs in a Canadian setting."],"pmcid":["PMC8890776"],"funding_grant_id":["U01DA038886","MSH-141971","R25 DA037756","U01 DA038886","SMN–139148","U01DA021525","U01 DA021525","U01-DA038886"],"pubmed_authors":["Hayashi K","DeBeck K","Christie D","Socias ME","Milloy MJ","Mackay L","Argento E","Choi J"],"additional_accession":[]},"is_claimable":false,"name":"Psychedelic use is associated with reduced daily opioid use among people who use illicit drugs in a Canadian setting.","description":"<h4>Background</h4>Research into the therapeutic and naturalistic uses of psychedelics for improving outcomes related to mental health disorders has generated increasing interest in recent years. While controlled clinical trials of psychedelics have signaled benefits for treating substance use disorders, this area has not been well studied in the context of naturalistic psychedelic use. This study sought to investigate the possible relationship between recent naturalistic psychedelic use and subsequent daily illicit opioid use among people who use drugs (PWUD).<h4>Methods</h4>Data (2006-2018) were drawn from three harmonized prospective cohorts of community-recruited PWUD in Vancouver, Canada. We used multivariable generalized linear mixed-effects modeling (GLMM) to estimate the independen","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2025-04-05T09:06:16.33Z","creation":"2025-04-05T09:06:16.33Z"},"accession":"S-EPMC8890776","cross_references":{"pubmed":["34758431"],"doi":["10.1016/j.drugpo.2021.103518"]}}