{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Napravnikova J"],"pubmed_abstract":["The control of strongylid infections has become challenging globally for equine practitioners due to the development of anthelmintic resistance. Comprehensive information on anthelmintic resistance in the Czech Republic, however, is still lacking. This study monitored the current efficacy of fenbendazole, pyrantel embonate, ivermectin and moxidectin. Forty-eight of 71 operations met the criteria (≥6 horses with ≥200 eggs per gram), with 969 fecal egg count reduction tests performed. Anthelmintic resistance was evaluated on an operation level based on fecal egg count reduction (FECR) and the lower limit of the 95% credible interval (LLCI) using Bayesian hierarchical models. General anthelmintic efficacy across all operations was assessed by posterior FECRs and the occurrence of sub-zero eff"],"journal":["Frontiers in veterinary science"],"pagination":["833204"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8899116"],"repository":["biostudies-literature"],"pubmed_title":["Total Failure of Fenbendazole to Control Strongylid Infections in Czech Horse Operations."],"pmcid":["PMC8899116"],"pubmed_authors":["Vadlejch J","Varady M","Napravnikova J"],"additional_accession":[]},"is_claimable":false,"name":"Total Failure of Fenbendazole to Control Strongylid Infections in Czech Horse Operations.","description":"The control of strongylid infections has become challenging globally for equine practitioners due to the development of anthelmintic resistance. Comprehensive information on anthelmintic resistance in the Czech Republic, however, is still lacking. This study monitored the current efficacy of fenbendazole, pyrantel embonate, ivermectin and moxidectin. Forty-eight of 71 operations met the criteria (≥6 horses with ≥200 eggs per gram), with 969 fecal egg count reduction tests performed. Anthelmintic resistance was evaluated on an operation level based on fecal egg count reduction (FECR) and the lower limit of the 95% credible interval (LLCI) using Bayesian hierarchical models. General anthelmintic efficacy across all operations was assessed by posterior FECRs and the occurrence of sub-zero eff","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-05T13:07:26.765Z","creation":"2025-04-05T13:07:26.765Z"},"accession":"S-EPMC8899116","cross_references":{"pubmed":["35265696"],"doi":["10.3389/fvets.2022.833204"]}}