biostudies-literatureUnknown75(5)Drawz PEMinnesota Department of HealthUsing vaccine data combined with electronic health records, we report that mRNA boosters provide greater protection than a 2-dose regimen against SARS-CoV-2 infection and related hospitalizations. The benefit of a booster was more evident in the elderly and those with comorbidities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America890-892https://www.ebi.ac.uk/biostudies/studies/S-EPMC8903410biostudies-literatureEffectiveness of BNT162b2 and mRNA-1273 Second Doses and Boosters for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and SARS-CoV-2-Related Hospitalizations: A Statewide Report From the Minnesota Electronic Health Record Consortium.PMC8903410Melendez VMcFarling LMuscoplat MHWaring SBodurtha PMurphy DVazquez Benitez GChamberlain AMWinkelman TNAKharbanda ABMurray ADeSilva MLupu RJohnson SGDudley RAMargolis KLDrawz PEfalseEffectiveness of BNT162b2 and mRNA-1273 Second Doses and Boosters for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and SARS-CoV-2-Related Hospitalizations: A Statewide Report From the Minnesota Electronic Health Record Consortium.Using vaccine data combined with electronic health records, we report that mRNA boosters provide greater protection than a 2-dose regimen against SARS-CoV-2 infection and related hospitalizations. The benefit of a booster was more evident in the elderly and those with comorbidities.2022-01-01T00:00:00Z2022 Sep2025-04-22T01:40:54.079Z2025-02-19T03:58:52.433ZS-EPMC89034103513702110.1093/cid/ciac110