biostudies-literatureTurnbull IBritish Heart FoundationCancer Research UKKadoorie Charitable FoundationMedical Research CouncilNational Natural Science Foundation of ChinaUniversity of OxfordNational Key Research and Development Program of ChinaWellcome Trust100415https://www.ebi.ac.uk/biostudies/studies/S-EPMC8904614biostudies-literatureUnknown21<h4>Background</h4>Widespread use of brain imaging in suspected stroke cases in Chinese adults has prompted the need for clinical adjudication studies of stroke types. We conducted a clinical adjudication study to assess the reporting and diagnostic accuracy of major stroke types.<h4>Methods</h4>The prospective China Kadoorie Biobank recruited >512,000 adults (mean age 52 years, 59% women) from 10 urban and rural areas in China during 2004-2008, and recorded 45,859 first-ever incident stroke cases during an 11-year follow-up. Medical records were retrieved in ∼85%, and clinical details were recorded using a handheld computer for specialist physician adjudicators who applied conventional WHO clinical criteria for diagnosis of stroke. The positive predictive value (PPV) for reported and adjuThe Lancet regional health. Western PacificDiagnostic accuracy of major stroke types in Chinese adults: A clinical adjudication study involving 40,000 stroke cases.PMC8904614MC_U1376868512016YFC0900500088158/Z/09/Z2016YFC0900501104085/Z/14/ZC16077/A29186CH/1996001/94542016YFC0900504202922/Z/16/Z2016YFC1303904212946/Z/18/Z91843302MC_UU_12026/2MC_UU_12026/2 MC_U13768685129186C500/A16896MC_UU_00017/1Yang LGuo YWright NTurnbull IClarke RKartsonaki CLi LLv JPei PGilbert SYu CChen ZChen YHacker ASansome SZhou JfalseDiagnostic accuracy of major stroke types in Chinese adults: A clinical adjudication study involving 40,000 stroke cases.<h4>Background</h4>Widespread use of brain imaging in suspected stroke cases in Chinese adults has prompted the need for clinical adjudication studies of stroke types. We conducted a clinical adjudication study to assess the reporting and diagnostic accuracy of major stroke types.<h4>Methods</h4>The prospective China Kadoorie Biobank recruited >512,000 adults (mean age 52 years, 59% women) from 10 urban and rural areas in China during 2004-2008, and recorded 45,859 first-ever incident stroke cases during an 11-year follow-up. Medical records were retrieved in ∼85%, and clinical details were recorded using a handheld computer for specialist physician adjudicators who applied conventional WHO clinical criteria for diagnosis of stroke. The positive predictive value (PPV) for reported and adju2022-01-01T00:00:00Z2022 Apr2025-04-04T23:34:10.004Z2025-04-04T23:34:10.004ZS-EPMC89046143528484810.1016/j.lanwpc.2022.100415