{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(3)"],"submitter":["Li L"],"pubmed_abstract":["<h4>Background</h4>Recurrent implantation failure (RIF) is a critical problem for assisted reproduction technology. High-quality embryos and the synchronization endometrium both have great significance. How to get the optimal endometrial receptivity is a challenge for implantation and pregnancy of infertile patients with RIF. The objective of this study is to investigate personalized protocol of frozen-thawed embryo transfer (FET) cycles, and its effect on clinical outcomes in patients with RIF.<h4>Methods</h4>We chose 91 RIF patients from January 2017 to June 2019 in the Reproductive Medicine Center of the First Hospital of Lanzhou University. A total of 100 FET cycles were undertaken with a gonadotropin-releasing hormone agonist (GnRH-agonist) protocol combined with hormone replacement t"],"journal":["Annals of translational medicine"],"pagination":["131"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8904980"],"repository":["biostudies-literature"],"pubmed_title":["Clinical outcomes of personalized frozen-thawed embryo transfer timing for patients with recurrent implantation failure."],"pmcid":["PMC8904980"],"pubmed_authors":["Liu L","Zhang X","Fu Y","Liang L","Li L","Kou Z"],"additional_accession":[]},"is_claimable":false,"name":"Clinical outcomes of personalized frozen-thawed embryo transfer timing for patients with recurrent implantation failure.","description":"<h4>Background</h4>Recurrent implantation failure (RIF) is a critical problem for assisted reproduction technology. High-quality embryos and the synchronization endometrium both have great significance. How to get the optimal endometrial receptivity is a challenge for implantation and pregnancy of infertile patients with RIF. The objective of this study is to investigate personalized protocol of frozen-thawed embryo transfer (FET) cycles, and its effect on clinical outcomes in patients with RIF.<h4>Methods</h4>We chose 91 RIF patients from January 2017 to June 2019 in the Reproductive Medicine Center of the First Hospital of Lanzhou University. A total of 100 FET cycles were undertaken with a gonadotropin-releasing hormone agonist (GnRH-agonist) protocol combined with hormone replacement t","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2025-04-27T03:21:27.535Z","creation":"2025-04-06T18:47:55.181Z"},"accession":"S-EPMC8904980","cross_references":{"pubmed":["35284554"],"doi":["10.21037/atm-22-161"]}}