biostudies-literatureSutherland RLNHMRC Career Development FellowshipHeart Foundation Future Leaders FellowshipNew South Wales Cancer Council ProgramHunter New England Clinical Research FellowNational Health and Medical Research Council (NHMRC) Translating Research into Practice fellowshipARC Discovery Early Career Researcher AwardThe Australian Prevention Partnership Centre962-979https://www.ebi.ac.uk/biostudies/studies/S-EPMC8907487biostudies-literatureUnknown80(4)<h4>Context</h4>Public health nutrition interventions shown to be effective under optimal research conditions need to be scaled up and implemented in real-world settings.<h4>Objectives</h4>The primary aim for this review was to assess the effectiveness of scaled-up public health nutrition interventions with proven efficacy, as examined in a randomized controlled trial. Secondary objectives were to: 1) determine if the effect size of scaled-up interventions were comparable to the prescale effect, and; 2) identify any adaptations made during the scale-up process.<h4>Data sources</h4>Six electronic databases were searched and field experts contacted.<h4>Study selection</h4>An intervention was considered scaled up if it was delivered on a larger scale than a preceding randomized controlled triNutrition reviewsA systematic review of adaptations and effectiveness of scaled-up nutrition interventions.PMC8907487APP1128348APP1150661101175PG 16–05DE170100382Brown AYoong SLByaruhanga JMilat AJSutherland RLNathan NKJackson JKMcLaughlin MLum MLane CMcCrabb SBauman AEWolfenden LfalseA systematic review of adaptations and effectiveness of scaled-up nutrition interventions.<h4>Context</h4>Public health nutrition interventions shown to be effective under optimal research conditions need to be scaled up and implemented in real-world settings.<h4>Objectives</h4>The primary aim for this review was to assess the effectiveness of scaled-up public health nutrition interventions with proven efficacy, as examined in a randomized controlled trial. Secondary objectives were to: 1) determine if the effect size of scaled-up interventions were comparable to the prescale effect, and; 2) identify any adaptations made during the scale-up process.<h4>Data sources</h4>Six electronic databases were searched and field experts contacted.<h4>Study selection</h4>An intervention was considered scaled up if it was delivered on a larger scale than a preceding randomized controlled tri2022-01-01T00:00:00Z2022 Mar2025-04-04T20:22:13.652Z2025-04-04T20:22:13.652ZS-EPMC89074873491971510.1093/nutrit/nuab096