biostudies-literatureUnknown9Cosmi B<h4>Importance</h4>The post-thrombotic syndrome (PTS) is the most common long-term complication of deep vein thrombosis (DVT), occurring in up to 40-50% of cases. There are limited evidence-based approaches for PTS clinical management.<h4>Objective</h4>To provide an expert consensus for PTS diagnosis, prevention, and treatment.<h4>Evidence-review</h4>MEDLINE, Cochrane Database review, and GOOGLE SCHOLAR were searched with the terms "post-thrombotic syndrome" and "post-phlebitic syndrome" used in titles and abstracts up to September 2020.<h4>Filters were</h4>English, Controlled Clinical Trial / Systematic Review / Meta-Analysis / Guideline. The relevant literature regarding PTS diagnosis, prevention and treatment was reviewed and summarized by the evidence synthesis team. On the basis of thFrontiers in cardiovascular medicine762443https://www.ebi.ac.uk/biostudies/studies/S-EPMC8907532biostudies-literatureThe Post-thrombotic Syndrome-Prevention and Treatment: VAS-European Independent Foundation in Angiology/Vascular Medicine Position Paper.PMC8907532Gresele PPrior MRighini MLessiani GWennberg PWStanek AKozak MLichtenberg MCatalano MKlein-Wegel PDe Marchi SCosmi BPecsvarady ZPuskas AFarkas KMarschang PKolluri RPoredos PSzuba AfalseThe Post-thrombotic Syndrome-Prevention and Treatment: VAS-European Independent Foundation in Angiology/Vascular Medicine Position Paper.<h4>Importance</h4>The post-thrombotic syndrome (PTS) is the most common long-term complication of deep vein thrombosis (DVT), occurring in up to 40-50% of cases. There are limited evidence-based approaches for PTS clinical management.<h4>Objective</h4>To provide an expert consensus for PTS diagnosis, prevention, and treatment.<h4>Evidence-review</h4>MEDLINE, Cochrane Database review, and GOOGLE SCHOLAR were searched with the terms "post-thrombotic syndrome" and "post-phlebitic syndrome" used in titles and abstracts up to September 2020.<h4>Filters were</h4>English, Controlled Clinical Trial / Systematic Review / Meta-Analysis / Guideline. The relevant literature regarding PTS diagnosis, prevention and treatment was reviewed and summarized by the evidence synthesis team. On the basis of th2022-01-01T00:00:00Z20222025-04-18T20:23:02.854Z2025-04-07T08:19:12.586ZS-EPMC89075323528235810.3389/fcvm.2022.762443