{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Ze LJ"],"funding":["National Natural Science Foundation of China"],"pubmed_abstract":["N-β-alanyldopamine (NBAD) is a precursor of N-acylquinone sclerotin utilized for cross-linking between cuticular proteins for cuticle during insect molting. The importance of NBAD in cuticle tanning has not been well compared among different developing stages of insects. <i>Henosepilachna vigintioctopunctata</i>, a typical polyphagous pest feeding on a large number of Solanaceae and Cucurbitaceae plants in Asian countries, displays diverse cuticle pigmentation patterns among developing stages and body regions. Here, we found that the expression of three genes (<i>Hvadc</i>, <i>Hvebony</i>, and <i>Hvtan</i>) involved in NBAD biosynthesis peaked in the 4-day-old pupae or 0-day-old adults of <i>H. vigintioctopunctata</i>. At the first, second, third, and fourth larval instar and pupal stage, "],"journal":["Frontiers in physiology"],"pagination":["829675"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8907826"],"repository":["biostudies-literature"],"pubmed_title":["Silencing of <i>Adc</i> and <i>Ebony</i> Causes Abnormal Darkening of Cuticle in <i>Henosepilachna vigintioctopunctata</i>."],"pmcid":["PMC8907826"],"pubmed_authors":["Ze LJ","Li GQ","Jin L"],"additional_accession":[]},"is_claimable":false,"name":"Silencing of <i>Adc</i> and <i>Ebony</i> Causes Abnormal Darkening of Cuticle in <i>Henosepilachna vigintioctopunctata</i>.","description":"N-β-alanyldopamine (NBAD) is a precursor of N-acylquinone sclerotin utilized for cross-linking between cuticular proteins for cuticle during insect molting. The importance of NBAD in cuticle tanning has not been well compared among different developing stages of insects. <i>Henosepilachna vigintioctopunctata</i>, a typical polyphagous pest feeding on a large number of Solanaceae and Cucurbitaceae plants in Asian countries, displays diverse cuticle pigmentation patterns among developing stages and body regions. Here, we found that the expression of three genes (<i>Hvadc</i>, <i>Hvebony</i>, and <i>Hvtan</i>) involved in NBAD biosynthesis peaked in the 4-day-old pupae or 0-day-old adults of <i>H. vigintioctopunctata</i>. At the first, second, third, and fourth larval instar and pupal stage, ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-04-08T17:50:40.038Z","creation":"2024-11-13T18:14:23.998Z"},"accession":"S-EPMC8907826","cross_references":{"pubmed":["35283776"],"doi":["10.3389/fphys.2022.829675"]}}