biostudies-literatureUnknown19(5)Fasola SMothers' knowledge about childhood asthma influences management practices and disease control, but validating knowledge/practice questionnaires is difficult due to the lack of a gold standard. We hypothesized that Latent Class Analysis (LCA) could help identify underlying mother profiles with similar knowledge/practices. A total of 438 mothers of asthmatic children answered a knowledge/practice questionnaire. Using answers to the knowledge/practice questionnaire as manifest variables, LCA identified two classes: Class 1, "poor knowledge" (33%); Class 2, "good knowledge" (67%). Classification accuracy was 0.96. Mothers in Class 2 were more likely to be aware of asthma-worsening factors and indicators of attacks. Mothers in Class 1 were more likely to prevent exposure to tobacco smoke (91.1%International journal of environmental research and public health2539https://www.ebi.ac.uk/biostudies/studies/S-EPMC8909612biostudies-literatureAsthma-Related Knowledge and Practices among Mothers of Asthmatic Children: A Latent Class Analysis.PMC8909612Licari AFasola SLa Grutta SCilluffo GMalizia VMontalbano LFerrante GfalseAsthma-Related Knowledge and Practices among Mothers of Asthmatic Children: A Latent Class Analysis.Mothers' knowledge about childhood asthma influences management practices and disease control, but validating knowledge/practice questionnaires is difficult due to the lack of a gold standard. We hypothesized that Latent Class Analysis (LCA) could help identify underlying mother profiles with similar knowledge/practices. A total of 438 mothers of asthmatic children answered a knowledge/practice questionnaire. Using answers to the knowledge/practice questionnaire as manifest variables, LCA identified two classes: Class 1, "poor knowledge" (33%); Class 2, "good knowledge" (67%). Classification accuracy was 0.96. Mothers in Class 2 were more likely to be aware of asthma-worsening factors and indicators of attacks. Mothers in Class 1 were more likely to prevent exposure to tobacco smoke (91.1%2022-01-01T00:00:00Z2022 Feb2025-04-18T12:09:45.028Z2025-04-06T21:50:56.592ZS-EPMC89096123527023210.3390/ijerph19052539