biostudies-literatureUnknown17(3)Plascencia Hernandez A<h4>Background</h4>Tuberculosis (TB) is a prevalent disease throughout the world. The extent of TB illness in childhood is not clear; recent data shows that 10-20% of the cases are found in children under 15 years old. In 2017, 1 million children developed the disease, of which 9% were co-infected with HIV.<h4>Methods</h4>A cross-sectional study that analyzed 48 children diagnosed with HIV-infection in Guadalajara, Mexico. The tuberculin skin test (TST) and QuantiFERON-TB Gold In-Tube test (QFT) were performed and compared to diagnose latent TB infection (LTBI).<h4>Results</h4>The average age was 9 years old (± 4), with an age range of 1-16 years; the 6-12-year-old group predominated with 50% of cases. 27 patients (56%) were male; 83% had received the BCG vaccination and 23% had a history PloS onee0264982https://www.ebi.ac.uk/biostudies/studies/S-EPMC8912134biostudies-literatureA prevalence study in Guadalajara, Mexico, comparing tuberculin skin test and QuantiFERON-TB Gold In-Tube.PMC8912134Sandoval Diaz MGonzalez Sanchez RMHernandez Canaveral IIGonzalez Diaz AGonzalez Ochoa ELuevanos Velazquez AMartinez Arce PAde Armas Rodriguez YPerez Gomez HRPlascencia Hernandez AfalseA prevalence study in Guadalajara, Mexico, comparing tuberculin skin test and QuantiFERON-TB Gold In-Tube.<h4>Background</h4>Tuberculosis (TB) is a prevalent disease throughout the world. The extent of TB illness in childhood is not clear; recent data shows that 10-20% of the cases are found in children under 15 years old. In 2017, 1 million children developed the disease, of which 9% were co-infected with HIV.<h4>Methods</h4>A cross-sectional study that analyzed 48 children diagnosed with HIV-infection in Guadalajara, Mexico. The tuberculin skin test (TST) and QuantiFERON-TB Gold In-Tube test (QFT) were performed and compared to diagnose latent TB infection (LTBI).<h4>Results</h4>The average age was 9 years old (± 4), with an age range of 1-16 years; the 6-12-year-old group predominated with 50% of cases. 27 patients (56%) were male; 83% had received the BCG vaccination and 23% had a history 2022-01-01T00:00:00Z20222026-03-27T16:42:11.02Z2025-04-04T09:10:09.146ZS-EPMC89121343527162510.1371/journal.pone.0264982