{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang K"],"funding":["National Natural Science Foundation of China","National Key Research and Development Program of China"],"pagination":["609"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8912397"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(5)"],"pubmed_abstract":["<i>Brassica napus</i> (oilseed rape) is one of the most important oil crops worldwide, but its growth is seriously threatened by <i>Sclerotinia sclerotiorum</i>. The mechanism of oilseed rape response to this pathogen has rarely been studied. Here, it was identified that BnaA03.MKK5 whose expression was induced by <i>S. sclerotiorum</i> infection was involved in plant immunity. <i>BnaA03.MKK5</i> overexpression lines exhibited decreased disease symptoms compared to wild-type plants, accompanied by the increased expression of camalexin-biosynthesis-related genes, including <i>BnPAD3</i> and <i>BnCYP71A13</i>. In addition, two copies of <i>BnMPK3</i> (<i>BnA06.MPK3</i> and <i>BnC03.MPK3</i>) were induced by <i>Sclerotinia</i> incubation, and BnaA03.MKK5 interacted with BnaA06.MPK3/BnaC03.MPK"],"journal":["Plants (Basel, Switzerland)"],"pubmed_title":["BnaA03.MKK5-BnaA06.MPK3/BnaC03.MPK3 Module Positively Contributes to <i>Sclerotinia sclerotiorum</i> Resistance in <i>Brassica napus</i>."],"pmcid":["PMC8912397"],"funding_grant_id":["2016YFD0100305","31376120"],"pubmed_authors":["Fu T","Wen J","Shen J","Ma C","Zhang K","Yi B","Tu J","Wang Z","Liu F","Zhuo C"],"additional_accession":[]},"is_claimable":false,"name":"BnaA03.MKK5-BnaA06.MPK3/BnaC03.MPK3 Module Positively Contributes to <i>Sclerotinia sclerotiorum</i> Resistance in <i>Brassica napus</i>.","description":"<i>Brassica napus</i> (oilseed rape) is one of the most important oil crops worldwide, but its growth is seriously threatened by <i>Sclerotinia sclerotiorum</i>. The mechanism of oilseed rape response to this pathogen has rarely been studied. Here, it was identified that BnaA03.MKK5 whose expression was induced by <i>S. sclerotiorum</i> infection was involved in plant immunity. <i>BnaA03.MKK5</i> overexpression lines exhibited decreased disease symptoms compared to wild-type plants, accompanied by the increased expression of camalexin-biosynthesis-related genes, including <i>BnPAD3</i> and <i>BnCYP71A13</i>. In addition, two copies of <i>BnMPK3</i> (<i>BnA06.MPK3</i> and <i>BnC03.MPK3</i>) were induced by <i>Sclerotinia</i> incubation, and BnaA03.MKK5 interacted with BnaA06.MPK3/BnaC03.MPK","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2026-04-08T17:35:59.882Z","creation":"2025-04-04T22:09:00.14Z"},"accession":"S-EPMC8912397","cross_references":{"pubmed":["35270079"],"doi":["10.3390/plants11050609"]}}