{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sanchez E"],"funding":["Diputació de Lleida and Generalitat de Catalunya"],"pagination":["1102"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8912766"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(5)"],"pubmed_abstract":["A large body of evidence demonstrates a relationship between hyperglycemia and increased concentrations of advanced glycation end-products (AGEs). However, there is little information about subcutaneous AGE accumulation in subjects with prediabetes, and whether or not this measurement could assist in the diagnosis of prediabetes is unclear. A cross-sectional study was conducted in 4181 middle-aged subjects without diabetes. Prediabetes (n = 1444) was defined as a glycosylated hemoglobin (HbA1c) level between 39 and 47 mmol/mol (5.7 to 6.4%), and skin autofluorescence (SAF) measurement was performed to assess AGEs. A multivariable logistic regression model and receiver operating characteristic curve were used. The cohort consisted of 50.1% women with an age of 57 [52;62] years, a BMI of 28."],"journal":["Nutrients"],"pubmed_title":["Weak Association between Skin Autofluorescence Levels and Prediabetes with an ILERVAS Cross-Sectional Study."],"pmcid":["PMC8912766"],"funding_grant_id":["2017SGR696 and SLT0021600250"],"pubmed_authors":["Sauret A","Castro-Boque E","Gavalda R","Torres G","Hernandez M","Fernandez E","Pamplona R","Farras-Salles C","Bermudez-Lopez M","Purroy F","Godoy P","Rius F","Lecube A","Mauricio D","Buti M","Sanchez E","Kerkeni M"],"additional_accession":[]},"is_claimable":false,"name":"Weak Association between Skin Autofluorescence Levels and Prediabetes with an ILERVAS Cross-Sectional Study.","description":"A large body of evidence demonstrates a relationship between hyperglycemia and increased concentrations of advanced glycation end-products (AGEs). However, there is little information about subcutaneous AGE accumulation in subjects with prediabetes, and whether or not this measurement could assist in the diagnosis of prediabetes is unclear. A cross-sectional study was conducted in 4181 middle-aged subjects without diabetes. Prediabetes (n = 1444) was defined as a glycosylated hemoglobin (HbA1c) level between 39 and 47 mmol/mol (5.7 to 6.4%), and skin autofluorescence (SAF) measurement was performed to assess AGEs. A multivariable logistic regression model and receiver operating characteristic curve were used. The cohort consisted of 50.1% women with an age of 57 [52;62] years, a BMI of 28.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-04-18T12:12:13.884Z","creation":"2025-04-06T21:48:13.838Z"},"accession":"S-EPMC8912766","cross_references":{"pubmed":["35268075"],"doi":["10.3390/nu14051102"]}}